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Nuclear Factor I/B (NFIB) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS713627

MBS713627 is an antibody targeting NFIB. Also known as Rabbit anti-human nuclear factor I/B polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$590 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
nuclear factor I/B (NFIB), Polyclonal Antibody
Full Product Name
Rabbit anti-human nuclear factor I/B polyclonal Antibody
Product Gene Name
anti-NFIB antibody
Product Synonym Names
nuclear factor I/B; NFIB; HMGIC/NFIB; NFI-RED; NFIB2; NFIB3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Molecular Weight
33,525 Da
OMIM
600728
Immunogen
Human NFIB
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-NFIB antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-NFIB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NFIB. It may not necessarily be applicable to this product.

NCBI GI #
12654879
NCBI GeneID
4781
NCBI Accession #
AAH01283.1
UniProt Secondary Accession #
O00166; Q12858; Q5VW29; Q63HM5; Q6ZNF9; Q96J45; G3V1P1; H7BYE8
UniProt Related Accession #
O00712
NCBI Official Full Name
Nuclear factor I/B
NCBI Official Synonym Full Names
nuclear factor I/B
NCBI Official Symbol
NFIB
NCBI Official Synonym Symbols
CTF; NF1-B; NFI-B; NFIB2; NFIB3; NF-I/B; NFI-RED; HMGIC/NFIB
UniProt Protein Name
Nuclear factor 1 B-type
UniProt Synonym Protein Names
CCAAT-box-binding transcription factor; CTF; Nuclear factor I/B; NF-I/B; NFI-B; TGGCA-binding protein
Protein Family
Nuclear factor
UniProt Gene Name
NFIB
UniProt Synonym Gene Names
NF1-B; Nuclear factor 1/B; CTF; NF-I/B; NFI-B
UniProt Entry Name
NFIB_HUMAN
NCBI Protein Information
nuclear factor 1 B-type; nuclear factor 1/B; TGGCA-binding protein; CCAAT-box-binding transcription factor

UniProt Comments for NFIB

NFI-B: Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 9p24.1

Cellular Component: nucleoplasm; nucleolus; nucleus

Molecular Function: DNA binding; double-stranded DNA binding

Biological Process: transcription from RNA polymerase II promoter; pontine nucleus development; glial cell differentiation; anterior commissure morphogenesis; chondrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; DNA replication; negative regulation of DNA binding; hindbrain development
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Research Articles on NFIB

1. Increased expression of NF1B is associated with pilocytic astrocytoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NFIB antibody

 Reference Product  PubMed Publications
 NFIX antibody  >21 publications with NFIB and NFIX
 NFIC antibody  >18 publications with NFIB and NFIC

Pathways associated with anti-NFIB antibody

 Products by Pathway  Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway antibodies  RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway Diagram
 RNA Polymerase III Abortive And Retractive Initiation Pathway antibodies  RNA Polymerase III Abortive And Retractive Initiation Pathway Diagram
 RNA Polymerase III Transcription Pathway antibodies  RNA Polymerase III Transcription Pathway Diagram
 RNA Polymerase III Transcription Termination Pathway antibodies  RNA Polymerase III Transcription Termination Pathway Diagram

Diseases associated with anti-NFIB antibody

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >33 publications with NFIB and Adenocarcinoma
 Carcinoma, Adenoid Cystic Antibodies  >33 publications with NFIB and Carcinoma, Adenoid Cystic
 Breast Neoplasms Antibodies  >14 publications with NFIB and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >5 publications with NFIB and Neoplasms, Experimental
 Nervous System Diseases Antibodies  >5 publications with NFIB and Nervous System Diseases
 Brain Diseases Antibodies  >3 publications with NFIB and Brain Diseases
 Carcinoma, Squamous Cell Antibodies  >3 publications with NFIB and Carcinoma, Squamous Cell
 Cell Transformation, Neoplastic Antibodies  >3 publications with NFIB and Cell Transformation, Neoplastic
 Lung Neoplasms Antibodies  >3 publications with NFIB and Lung Neoplasms
 Abnormalities, Drug-Induced Antibodies  >1 publications with NFIB and Abnormalities, Drug-Induced

Organs/Tissues associated with anti-NFIB antibody

 Organ/Tissue Name  Pubmed Publications
 Salivary Gland Antibodies  >29 publications with NFIB and Salivary Gland
 Brain Antibodies  >27 publications with NFIB and Brain
 Lung Antibodies  >13 publications with NFIB and Lung
 Embryonic Tissue Antibodies  >9 publications with NFIB and Embryonic Tissue
 Bone Antibodies  >8 publications with NFIB and Bone
 Nerve Antibodies  >6 publications with NFIB and Nerve
 Muscle Antibodies  >5 publications with NFIB and Muscle
 Skin Antibodies  >5 publications with NFIB and Skin
 Eye Antibodies  >5 publications with NFIB and Eye
 Mouth Antibodies  >4 publications with NFIB and Mouth
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