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Anoctamin 2 (ANO2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS714387

Rabbit polyclonal to ANO2 Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which… More details

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Product Overview

Online Datasheet in PDF
Product Name
anoctamin 2 (ANO2), Polyclonal Antibody
Full Product Name
Rabbit anti-human anoctamin 2 polyclonal Antibody
Product Gene Name
Product Synonym Names
anoctamin 2; ANO2; C12orf3; DKFZp434P102; TMEM16B
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid ; PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Purity/Purification
Antigen affinity purification
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
OMIM
610109
3D Structure
ModBase 3D Structure for Q9NQ90
Immunogen
Human ANO2
Product Type
Purified Rabbit Anti- Human PolyClonal Antibody
Immunogen Species
Homo Sapiens (Human)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-169622 / sc-292004
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ANO2 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

Western Blot of anti-ANO2 antibody

All lanes: anoctamin 2 antibody at 2ug/ml+ mouse brain tissue secondary Secondary
Goat polyclonal to Rabbit IgG at 1/15000 dilution
Predicted band size : 114 kDa
Observed band size: 114 kDa
Rabbit Anti-ANO2 Polyclonal Antibody – Cat# MBS714387

Immunohistochemistry of anti-ANO2 antibody

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using MBS714387 at dilution 1:50.
Rabbit Anti-ANO2 Polyclonal Antibody, Immunohistochemistry – Cat# MBS714387

Immunofluorescence of anti-ANO2 antibody

Immunofluorescent analysis of HepG2 cells, using MBS714387 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Rabbit Anti-ANO2 Polyclonal Antibody, Immunofluorescence – Cat# MBS714387

Immunoprecipitation of anti-ANO2 antibody

IP Result of anti-ANO2 (IP: MBS714387 , 4ug; Detection: MBS714387 1:300) with mouse brain tissue lysate 10000ug.
Rabbit Anti-ANO2 Polyclonal Antibody, Immunoprecipitation – Cat# MBS714387

Other Notes

Small volumes of anti-ANO2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ANO2 purchase

MBS714387 is an antibody targeting ANO2. Also known as Rabbit anti-human anoctamin 2 polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ANO2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
anoctamin-2 isoform 2
NCBI Official Synonym Full Names
anoctamin 2, calcium activated chloride channel
NCBI Official Symbol
ANO2
NCBI Official Synonym Symbols
C12orf3; TMEM16B
UniProt Protein Name
Anoctamin-2
UniProt Synonym Protein Names
Transmembrane protein 16B
Protein Family
UniProt Gene Name
ANO2
UniProt Synonym Gene Names
C12orf3; TMEM16B
UniProt Entry Name
ANO2_HUMAN
NCBI Protein Information
anoctamin-2; transmembrane protein 16B (eight membrane-spanning domains)

NCBI Summary for ANO2

ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).[supplied by OMIM, Jan 2011]

UniProt Comments for ANO2

ANO2: Acts as a calcium-activated chloride channel (CaCC), mostly in photoreceptors. May mediate olfactory amplification in olfactory sensory neurons (OSNs) and light perception amplification in retina. Belongs to the anoctamin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transporter, ion channel; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: 12p13.3

Cellular Component: nucleoplasm; nonmotile primary cilium; plasma membrane

Molecular Function: protein homodimerization activity; intracellular calcium activated chloride channel activity; protein heterodimerization activity

Biological Process: transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ANO2 antibody

 Reference Product  PubMed Publications
 CLCA2 antibody  >1 publications with ANO2 and CLCA2

Diseases associated with anti-ANO2 antibody

Organs/Tissues associated with anti-ANO2 antibody

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