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Alcohol Dehydrogenase [NADP (+)] (AKR1A1) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS717623

This gene encodes a member of the aldoketo reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in… More details

$1035 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Alcohol dehydrogenase [NADP (+)] (Akr1a1), Recombinant Protein
Full Product Name
Recombinant Rat Alcohol dehydrogenase [NADP (+)] (Akr1a1)
Sequence
TASSVLLHTG QKMPLIGLGT WKSEPGQVKA AIKYALSVGY RHIDCASVYG NETEIGEALK ESVGAGKAVP REELFVTSKL WNTKHHPEDV EPAVRKTLAD LQLEYLDLYL MHWPYAFERG DNPFPKNADG TVKYDSTHYK ETWKALEALV AKGLVKALGL SNFSSRQIDD VLSVASVRPA VLQVECHPYL AQNELIAHCQ ARGLEVTAYS PLGSSDRAWR HPDEPVLLEE PVVLALAEKH GRSPAQILLR WQVQRKVICI PKSITPSRIL QNIQVFDFTF SPEEMKQLDA LNKNWRYIVP MITVDGKRVP RDAGHPLYPF NDPY
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
36,506 Da
Sequence Positions
2-325, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P51635
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Akr1a1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Akr1a1 purchase

MBS717623 is a recombinant protein targeting Akr1a1. Also known as Recombinant Rat Alcohol dehydrogenase [NADP (+)] (Akr1a1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Akr1a1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
alcohol dehydrogenase
NCBI Official Synonym Full Names
aldo-keto reductase family 1 member A1
NCBI Official Symbol
Akr1a1
NCBI Official Synonym Symbols
Akr1a4
UniProt Protein Name
Alcohol dehydrogenase [NADP(+)]
UniProt Synonym Protein Names
3-DG-reducing enzyme; Aldehyde reductase; Aldo-keto reductase family 1 member A1
Protein Family
UniProt Gene Name
Akr1a1
UniProt Synonym Gene Names
Alr
NCBI Protein Information
alcohol dehydrogenase [NADP(+)]

NCBI Summary for Akr1a1

enzyme that catalyzes the NADPH-dependent reduction of 3-deoxyglucosone; important for detoxifying 3-deoxyglucosone when it is formed through the Maillard reaction in vivo [RGD, Feb 2006]

UniProt Comments for Akr1a1

Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs (). Catalyzes the NADPH-dependent reduction of 3-deoxyglucosone (3-DG).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Akr1a1 recombinant protein

 Reference Product  PubMed Publications
 Aldh1a3 recombinant protein  >1 publications with Akr1a1 and Aldh1a3
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