Protein Kinase Inhibitor Beta (PKIb) ELISA Kit for Human

Name: Human PKIb ELISA Kit; Protein Kinase Inhibitor Beta; MyBioSource
Brand: MyBioSource
SKU: MBS729692
Price: 580 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS729692

MBS729692 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Protein Kinase Inhibitor Beta (PKIb) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$580 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Protein Kinase Inhibitor Beta (PKIb), ELISA Kit

Full Product Name

Human Protein Kinase Inhibitor Beta ELISA Kit

Product Gene Name

PKIb elisa kit

Species Reactivity

Human

Assay Type

Competitive

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

0.5-10ng/mL

Sensitivity

0.1ng/mL

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

8,468 Da

Chromosome Location

Chromosome: 6; NC_000006.11 (122793062..123047518). Location: 6q22.31

OMIM

606914

3D Structure

ModBase 3D Structure for Q9C010

Sample Preparation

We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Product Categories/Family for PKIb elisa kit

Signal Transduction

ISO Certification

Manufactured in an ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of PKIb elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PKIb. It may not necessarily be applicable to this product.

NCBI GI #

55959914

NCBI GeneID

5570

UniProt Primary Accession #

Q9C010

UniProt Secondary Accession #

Q567T9; B2RCK2

UniProt Related Accession #

Q5T0Z6; Q5T0Z7; Q9C010

NCBI Official Full Name

protein kinase (cAMP-dependent, catalytic) inhibitor beta

NCBI Official Synonym Full Names

protein kinase (cAMP-dependent, catalytic) inhibitor beta

NCBI Official Symbol

PKIB

NCBI Official Synonym Symbols

PRKACN2; FLJ23817

UniProt Protein Name

cAMP-dependent protein kinase inhibitor beta

Protein Family

cAMP-dependent protein kinase

UniProt Gene Name

PKIB

UniProt Synonym Gene Names

PRKACN2

UniProt Entry Name

IPKB_HUMAN

NCBI Protein Information

cAMP-dependent protein kinase inhibitor beta; PKI-beta; OTTHUMP00000017114; OTTHUMP00000017116; cAMP-dependent protein kinase inhibitor 2

NCBI Summary for PKIb

The protein encoded by this gene is a member of the cAMP-dependent protein kinase inhibitor family. Studies of a similar protein in rat suggest that this protein may interact with the catalytic subunit of cAMP-dependent protein kinase and act as a competitive inhibitor. At least three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq]

UniProt Comments for PKIb

PKIB: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. Belongs to the PKI family.

Protein type: Inhibitor; Protein kinase, regulatory subunit

Chromosomal Location of Human Ortholog: 6q22.31

Cellular Component: cytoplasm; nucleus

Molecular Function: cAMP-dependent protein kinase inhibitor activity

Research Articles on PKIb

1. Findings show that PKIB and PKA-C kinase can have critical functions of aggressive phenotype of PCs through Akt phosphorylation and that they should be a promising molecular target for PC treatment.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PKIb elisa kit

Products by Pathway	Pathway Diagram
Calcium Regulation In The Cardiac Cell Pathway antibodies	Calcium Regulation In The Cardiac Cell Pathway Diagram
Myometrial Relaxation And Contraction Pathways antibodies	Myometrial Relaxation And Contraction Pathways Diagram

Diseases associated with PKIb elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>3 publications with PKIb and Neoplasms
Eye Abnormalities Antibodies	>1 publications with PKIb and Eye Abnormalities
Congenital Abnormalities Antibodies	>1 publications with PKIb and Congenital Abnormalities
Nervous System Diseases Antibodies	>1 publications with PKIb and Nervous System Diseases
Pneumonia Antibodies	>1 publications with PKIb and Pneumonia
Neoplasm Metastasis Antibodies	>1 publications with PKIb and Neoplasm Metastasis
Glioma Antibodies	>1 publications with PKIb and Glioma
Pancreatic Neoplasms Antibodies	>1 publications with PKIb and Pancreatic Neoplasms
Prostatic Neoplasms Antibodies	>1 publications with PKIb and Prostatic Neoplasms
Inflammation Antibodies	>1 publications with PKIb and Inflammation

Organs/Tissues associated with PKIb elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>5 publications with PKIb and Brain
Testis Antibodies	>4 publications with PKIb and Testis
Nerve Antibodies	>1 publications with PKIb and Nerve
Skin Antibodies	>1 publications with PKIb and Skin
Prostate Antibodies	>1 publications with PKIb and Prostate
Eye Antibodies	>1 publications with PKIb and Eye
Placenta Antibodies	>1 publications with PKIb and Placenta