Adenylate Cyclase 1, Brain (ADCY1) ELISA Kit for Mouse

This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

ADCY1: a calmodulin-sensitive adenylyl cyclase expressed in brain. The mouse protein is involved in pattern formation of the brain. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.

Protein type: Nucleotide Metabolism - purine; Adenylyl cyclase; Transporter; Membrane protein, multi-pass; Transporter, aquaporin family; EC 4.6.1.1; Lyase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7p12.3

Cellular Component: cytoplasm; plasma membrane; integral to membrane; nucleus

Molecular Function: calmodulin binding; metal ion binding; calcium- and calmodulin-responsive adenylate cyclase activity; ATP binding

Biological Process: response to drug; epidermal growth factor receptor signaling pathway; circadian rhythm; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; response to lithium ion; water transport; activation of protein kinase A; signal transduction; regulation of circadian rhythm; G-protein signaling, adenylate cyclase activating pathway; synaptic transmission; axonogenesis; long-term memory; phospholipase C activation; energy reserve metabolic process; renal water homeostasis; innate immune response; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; transmembrane transport

Disease: Deafness, Autosomal Recessive 44