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Leukotriene B4 Receptor 1 (LTB4R) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS762453

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Human LTB4Rantibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human LTB4R antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Leukotriene B4 receptor 1 (LTB4R), ELISA Kit
Full Product Name
Human Leukotriene B4 receptor 1 ELISA Kit
Product Gene Name
LTB4R elisa kit
Product Synonym Names
LTB4R/Leukotriene B4 receptor 1/LTB4-R 1/LTB4-R1//P2Y purinoceptor 7/P2Y7/Chemoattractant receptor-like 1/G-protein coupled receptor 16/BLT1/LTB4R1/chemokine receptor-like 1/CMKRL1/leukotriene B4 receptor/LTBR1/purinergic receptor P2Y; G-protein coupled; 7
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
0.781-50ng/ml
Sensitivity
0.469ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
37,557 Da
OMIM
601531
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of LTB4R elisa kit

Human LTB4R ELISA Kit – Cat# MBS762453

Typical Standard Curve of LTB4R elisa kit

Human LTB4R ELISA Kit, Typical Standard Curve – Cat# MBS762453

Other Notes

Small volumes of LTB4R elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LTB4R purchase

MBS762453 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Leukotriene B4 receptor 1 (LTB4R) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LTB4R. The ELISA analytical biochemical technique of the MBS762453 kit is based on LTB4R antibody-LTB4R antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LTB4R antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LTB4R. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for LTB4R. It may not necessarily be applicable to this product.

NCBI GI #
221218998
NCBI GeneID
1241
NCBI Accession #
NP_001137391.1
UniProt Secondary Accession #
Q13305; Q53XV5; Q92641; Q9BSU5
UniProt Related Accession #
Q15722
GenBank Nucleotide #
NM_001143919.2
NCBI Official Full Name
leukotriene B4 receptor 1
NCBI Official Synonym Full Names
leukotriene B4 receptor
NCBI Official Symbol
LTB4R
NCBI Official Synonym Symbols
BLT1; BLTR; P2Y7; GPR16; LTBR1; P2RY7; CMKRL1; LTB4R1
UniProt Protein Name
Leukotriene B4 receptor 1
UniProt Synonym Protein Names
Chemoattractant receptor-like 1; G-protein coupled receptor 16; P2Y purinoceptor 7; P2Y7
Protein Family
Leukotriene B4 receptor
UniProt Gene Name
LTB4R
UniProt Synonym Gene Names
BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7; LTB4-R 1; LTB4-R1; P2Y7
UniProt Entry Name
LT4R1_HUMAN
NCBI Protein Information
leukotriene B4 receptor 1

UniProt Comments for LTB4R

LTB4R: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR

Chromosomal Location of Human Ortholog: 14q11.2-q12

Cellular Component: integral to plasma membrane; lipid raft; plasma membrane

Molecular Function: leukotriene B4 receptor activity; leukotriene receptor activity; nucleotide binding; peptide receptor activity, G-protein coupled

Biological Process: cell motility; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); immune response; inflammatory response; muscle contraction; neuropeptide signaling pathway
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Research Articles on LTB4R

1. The BLT1 Inhibitory Function of alpha-1 Antitrypsin Augmentation Therapy Disrupts Leukotriene B4 Neutrophil Signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with LTB4R elisa kit

 Reference Product  PubMed Publications
 CYSLTR1 elisa kit  >1 publications with LTB4R and CYSLTR1
 CCK elisa kit  >1 publications with LTB4R and CCK

Pathways associated with LTB4R elisa kit

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Eicosanoid Ligand-binding Receptors Pathway antibodies  Eicosanoid Ligand-binding Receptors Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Leukotriene Receptors Pathway antibodies  Leukotriene Receptors Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with LTB4R elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >39 publications with LTB4R and Inflammation
 Asthma Antibodies  >17 publications with LTB4R and Asthma
 Necrosis Antibodies  >8 publications with LTB4R and Necrosis
 Cardiovascular Diseases Antibodies  >5 publications with LTB4R and Cardiovascular Diseases
 Fibrosis Antibodies  >3 publications with LTB4R and Fibrosis
 Disease Models, Animal Antibodies  >3 publications with LTB4R and Disease Models, Animal
 Ovarian Neoplasms Antibodies  >2 publications with LTB4R and Ovarian Neoplasms
 Leukemia Antibodies  >2 publications with LTB4R and Leukemia
 Lung Neoplasms Antibodies  >1 publications with LTB4R and Lung Neoplasms
 Hyperplasia Antibodies  >1 publications with LTB4R and Hyperplasia

Organs/Tissues associated with LTB4R elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >51 publications with LTB4R and Blood
 Lung Antibodies  >17 publications with LTB4R and Lung
 Skin Antibodies  >5 publications with LTB4R and Skin
 Bone Marrow Antibodies  >5 publications with LTB4R and Bone Marrow
 Kidney Antibodies  >3 publications with LTB4R and Kidney
 Spleen Antibodies  >2 publications with LTB4R and Spleen
 Uterus Antibodies  >2 publications with LTB4R and Uterus
 Eye Antibodies  >1 publications with LTB4R and Eye
 Ovary Antibodies  >1 publications with LTB4R and Ovary
 Brain Antibodies  >1 publications with LTB4R and Brain
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