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C-C Chemokine Receptor Type 6 (CCR6) ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS762461

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. anti-Mouse Ccr6 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Mouse Ccr6 antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C-C chemokine receptor type 6 (Ccr6), ELISA Kit
Full Product Name
Mouse C-C chemokine receptor type 6 ELISA Kit
Product Gene Name
Ccr6 elisa kit
Product Synonym Names
Ccr6/GPR-CY4/STRL22/BN-1/CC-CKR-6/CCR-6/CD196 antigen/chemokine (C-C motif) receptor 6/CKR-L3G-protein coupled receptor 29/CKRL3LARC receptor/CMKBR6/DRY6/GPR29/C-C CKR-6/DRY-6/lymphocyte; 22
Species Reactivity
Mouse
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
42,494 Da
OMIM
601835
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of Ccr6 elisa kit

Mouse CCR6 ELISA Kit – Cat# MBS762461

Typical Standard Curve of Ccr6 elisa kit

Mouse CCR6 ELISA Kit, Typical Standard Curve – Cat# MBS762461

Other Notes

Small volumes of Ccr6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ccr6 purchase

MBS762461 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the C-C chemokine receptor type 6 (Ccr6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Ccr6. The ELISA analytical biochemical technique of the MBS762461 kit is based on Ccr6 antibody-Ccr6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Ccr6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Ccr6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for Ccr6. It may not necessarily be applicable to this product.

NCBI GI #
37188165
NCBI GeneID
1235
NCBI Accession #
NP_113597.2
UniProt Secondary Accession #
P78553; Q92846; E1P5C6
UniProt Related Accession #
P51684
GenBank Nucleotide #
NM_031409.3
NCBI Official Full Name
C-C chemokine receptor type 6
NCBI Official Synonym Full Names
chemokine (C-C motif) receptor 6
NCBI Official Symbol
CCR6
NCBI Official Synonym Symbols
BN-1; DCR2; DRY6; CCR-6; CD196; CKRL3; GPR29; CKR-L3; CMKBR6; GPRCY4; STRL22; CC-CKR-6; C-C CKR-6
UniProt Protein Name
C-C chemokine receptor type 6
UniProt Synonym Protein Names
Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptor; CD_antigen: CD196
Protein Family
C-C chemokine receptor
UniProt Gene Name
CCR6
UniProt Synonym Gene Names
CKRL3; CMKBR6; GPR29; STRL22; C-C CKR-6; CC-CKR-6; CCR-6; CKR-L3; GPRCY4
UniProt Entry Name
CCR6_HUMAN
NCBI Protein Information
C-C chemokine receptor type 6

NCBI Summary for Ccr6

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for Ccr6

CCR6: Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, integral; Motility/polarity/chemotaxis; Membrane protein, multi-pass; GPCR, family 1

Chromosomal Location of Human Ortholog: 6q27

Cellular Component: cell surface; cytosol; integral to plasma membrane; plasma membrane

Molecular Function: C-C chemokine receptor activity; chemokine receptor activity; receptor activity

Biological Process: cell motility; cellular defense response; chemotaxis; dendritic cell chemotaxis; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; humoral immune response; immune response; innate immune response; signal transduction
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Research Articles on Ccr6

1. The data reviewed suggest the necessity of evaluation of other blood redox-balance and nitric oxide in psoriasis should with additional investigations to targeting CCR6 rs3093024 in the genetic susceptibility of psoriasis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Ccr6 elisa kit

 Reference Product  PubMed Publications
 CCL20 elisa kit  >417 publications with Ccr6 and CCL20
 CXCR5 elisa kit  >75 publications with Ccr6 and CXCR5
 CCL19 elisa kit  >47 publications with Ccr6 and CCL19
 CCL21 elisa kit  >44 publications with Ccr6 and CCL21
 CXCL12 elisa kit  >37 publications with Ccr6 and CXCL12
 CXCL10 elisa kit  >35 publications with Ccr6 and CXCL10
 CCL25 elisa kit  >14 publications with Ccr6 and CCL25
 IL8 elisa kit  >6 publications with Ccr6 and IL8
 CCL27 elisa kit  >5 publications with Ccr6 and CCL27
 DEFB1 elisa kit  >4 publications with Ccr6 and DEFB1

Pathways associated with Ccr6 elisa kit

 Products by Pathway  Pathway Diagram
 Beta Defensins Pathway antibodies  Beta Defensins Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Defensins Pathway antibodies  Defensins Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram

Diseases associated with Ccr6 elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >301 publications with Ccr6 and Inflammation
 Necrosis Antibodies  >122 publications with Ccr6 and Necrosis
 Arthritis, Rheumatoid Antibodies  >86 publications with Ccr6 and Arthritis, Rheumatoid
 Lung Diseases Antibodies  >74 publications with Ccr6 and Lung Diseases
 Hypersensitivity Antibodies  >56 publications with Ccr6 and Hypersensitivity
 Liver Diseases Antibodies  >50 publications with Ccr6 and Liver Diseases
 Cardiovascular Diseases Antibodies  >33 publications with Ccr6 and Cardiovascular Diseases
 Neoplasm Metastasis Antibodies  >31 publications with Ccr6 and Neoplasm Metastasis
 Death Antibodies  >23 publications with Ccr6 and Death
 Kidney Diseases Antibodies  >20 publications with Ccr6 and Kidney Diseases

Organs/Tissues associated with Ccr6 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >772 publications with Ccr6 and Blood
 Lymph Node Antibodies  >117 publications with Ccr6 and Lymph Node
 Intestine Antibodies  >85 publications with Ccr6 and Intestine
 Bone Marrow Antibodies  >59 publications with Ccr6 and Bone Marrow
 Spleen Antibodies  >58 publications with Ccr6 and Spleen
 Thymus Antibodies  >32 publications with Ccr6 and Thymus
 Pharynx Antibodies  >15 publications with Ccr6 and Pharynx
 Stomach Antibodies  >8 publications with Ccr6 and Stomach
 Prostate Antibodies  >6 publications with Ccr6 and Prostate
 Mammary Gland Antibodies  >1 publications with Ccr6 and Mammary Gland
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