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Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS764501

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti- HNRNPK antibody was pre-coated onto 96-well plates. And the biotin conjugated anti- HNRNPK antibody was used as detection antibodies. The standards,… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Heterogeneous nuclear ribonucleoprotein K (HNRNPK), ELISA Kit
Full Product Name
Human Heterogeneous nuclear ribonucleoprotein K ELISA Kit
Product Gene Name
HNRNPK elisa kit
Product Synonym Names
HNRNPK/HNRPK/Heterogeneous nuclear ribonucleoprotein K/Transformation up-regulated nuclear protein/TUNP
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
39.063-2500pg/ml
Sensitivity
23.438pg/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
50,976 Da
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of HNRNPK elisa kit

Human HNRNPK ELISA Kit – Cat# MBS764501

Typical Standard Curve of HNRNPK elisa kit

Human HNRNPK ELISA Kit, Typical Standard Curve – Cat# MBS764501

Other Notes

Small volumes of HNRNPK elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HNRNPK purchase

MBS764501 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Heterogeneous nuclear ribonucleoprotein K (HNRNPK) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HNRNPK. The ELISA analytical biochemical technique of the MBS764501 kit is based on HNRNPK antibody-HNRNPK antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HNRNPK antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HNRNPK. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for HNRNPK. It may not necessarily be applicable to this product.

NCBI GI #
16923998
NCBI GeneID
117282
NCBI Accession #
NP_476482.1
UniProt Secondary Accession #
Q07244; Q15671; Q60577; Q922Y7; Q96J62
UniProt Related Accession #
P61980
GenBank Nucleotide #
NM_057141.1
NCBI Official Full Name
heterogeneous nuclear ribonucleoprotein K
NCBI Official Synonym Full Names
heterogeneous nuclear ribonucleoprotein K
NCBI Official Symbol
Hnrnpk
NCBI Official Synonym Symbols
Csbp; Hnrpk
UniProt Protein Name
Heterogeneous nuclear ribonucleoprotein K
UniProt Synonym Protein Names
dC stretch-binding protein; CSBP
Protein Family
Heterogeneous nuclear ribonucleoprotein
UniProt Gene Name
Hnrnpk
UniProt Synonym Gene Names
Hnrpk; hnRNP K; CSBP
UniProt Entry Name
HNRPK_RAT
NCBI Protein Information
heterogeneous nuclear ribonucleoprotein K

NCBI Summary for HNRNPK

DNA and pre-mRNA binding protein, binds primarily with cytidine-rich (poly-C) sequences [RGD, Feb 2006]

UniProt Comments for HNRNPK

hnRNP K: a heterogeneous nuclear ribonucleoprotein (hnRNP). One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Two alternatively spliced isoforms have been described.

Protein type: RNA-binding; Spliceosome; RNA splicing

Cellular Component: cell cortex; cell junction; cytosol; dendritic spine; focal adhesion; membrane; mitochondrion; nerve terminal; nuclear chromatin; nucleoplasm; nucleus; podosome; postsynaptic density; spliceosome

Molecular Function: actinin binding; ATPase binding; double-stranded DNA binding; heat shock protein binding; lamin binding; mRNA 3'-UTR binding; pre-mRNA 3'-splice site binding; protein binding; protein domain specific binding; ribonucleoprotein binding; RNA binding; single-stranded DNA binding; transcription factor binding

Biological Process: acute-phase response; aging; camera-type eye development; cellular response to insulin stimulus; central nervous system development; cerebellum development; cerebral cortex development; hippocampus development; kidney development; liver development; lung development; mRNA processing; negative regulation of apoptosis; negative regulation of nuclear mRNA splicing, via spliceosome; negative regulation of protein binding; negative regulation of transcription from RNA polymerase II promoter; ovarian follicle development; peripheral nervous system development; positive regulation of low-density lipoprotein receptor biosynthetic process; positive regulation of receptor-mediated endocytosis; positive regulation of RNA splicing; positive regulation of synaptic transmission; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; response to activity; RNA splicing; thymus development; transcription from RNA polymerase II promoter; transcription, DNA-dependent
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Research Articles on HNRNPK

1. hnRNP K regulates dendritic spine density and long-term potentiation in cultured hippocampal neurons from embryonic rats. hnRNP K knockdown prevents ERK cascade activation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HNRNPK elisa kit

 Reference Product  PubMed Publications
 Hnrnpm elisa kit  >3 publications with HNRNPK and Hnrnpm
 Hnrnpa2b1 elisa kit  >3 publications with HNRNPK and Hnrnpa2b1
 Hnrnpr elisa kit  >1 publications with HNRNPK and Hnrnpr
 Hnrnpa1 elisa kit  >1 publications with HNRNPK and Hnrnpa1
 Hnrnpf elisa kit  >1 publications with HNRNPK and Hnrnpf

Pathways associated with HNRNPK elisa kit

 Products by Pathway  Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 SUMO E3 Ligases SUMOylate Target Proteins Pathway antibodies  SUMO E3 Ligases SUMOylate Target Proteins Pathway Diagram

Diseases associated with HNRNPK elisa kit

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >4 publications with HNRNPK and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >4 publications with HNRNPK and Neoplasms, Experimental
 Liver Neoplasms, Experimental Antibodies  >3 publications with HNRNPK and Liver Neoplasms, Experimental
 Disease Models, Animal Antibodies  >3 publications with HNRNPK and Disease Models, Animal
 Liver Neoplasms Antibodies  >3 publications with HNRNPK and Liver Neoplasms
 Neurobehavioral Manifestations Antibodies  >3 publications with HNRNPK and Neurobehavioral Manifestations
 Precancerous Conditions Antibodies  >3 publications with HNRNPK and Precancerous Conditions
 Fibrosis Antibodies  >2 publications with HNRNPK and Fibrosis
 Carcinoma, Hepatocellular Antibodies  >2 publications with HNRNPK and Carcinoma, Hepatocellular
 Abnormalities, Multiple Antibodies  >2 publications with HNRNPK and Abnormalities, Multiple

Organs/Tissues associated with HNRNPK elisa kit

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >7 publications with HNRNPK and Liver
 Kidney Antibodies  >5 publications with HNRNPK and Kidney
 Brain Antibodies  >5 publications with HNRNPK and Brain
 Lung Antibodies  >4 publications with HNRNPK and Lung
 Colon Antibodies  >3 publications with HNRNPK and Colon
 Testis Antibodies  >3 publications with HNRNPK and Testis
 Embryonic Tissue Antibodies  >3 publications with HNRNPK and Embryonic Tissue
 Heart Antibodies  >2 publications with HNRNPK and Heart
 Prostate Antibodies  >2 publications with HNRNPK and Prostate
 Ovary Antibodies  >1 publications with HNRNPK and Ovary
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