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Corticotropin-Releasing Factor Receptor 1 (CRHR1) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS764896

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Human CRHR1antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human CRHR1 antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Corticotropin-releasing factor receptor 1 (CRHR1), ELISA Kit
Full Product Name
Human Corticotropin-releasing factor receptor 1 ELISA Kit
Product Gene Name
CRHR1 elisa kit
Product Synonym Names
CRHR1/Corticotropin-releasing factor receptor 1/Corticotropin-releasing hormone receptor 1/CRF-R-1/CRF-R1/CRFR-1/CRH-R-1/CRH-R1/seven transmembrane helix receptor/CRF1/CRFR/CRHR1f/CRH-R1h/CRHR1L/CRHRCRH-R1
Species Reactivity
Human
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
0.313-20ng/ml
Sensitivity
0.188ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
28,122 Da
OMIM
122561
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of CRHR1 elisa kit

Human CRHR1 ELISA Kit – Cat# MBS764896

Typical Standard Curve of CRHR1 elisa kit

Human CRHR1 ELISA Kit, Typical Standard Curve – Cat# MBS764896

Other Notes

Small volumes of CRHR1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CRHR1 purchase

MBS764896 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Corticotropin-releasing factor receptor 1 (CRHR1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CRHR1. The ELISA analytical biochemical technique of the MBS764896 kit is based on CRHR1 antibody-CRHR1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CRHR1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CRHR1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CRHR1. It may not necessarily be applicable to this product.

NCBI GI #
223717971
NCBI GeneID
1394
NCBI Accession #
NP_001138618.1
UniProt Secondary Accession #
Q13008; Q4QRJ1; Q9UK64; B4DIE9
UniProt Related Accession #
P34998
GenBank Nucleotide #
NM_001145146.1
NCBI Official Full Name
corticotropin-releasing factor receptor 1 isoform 1
NCBI Official Synonym Full Names
corticotropin releasing hormone receptor 1
NCBI Official Symbol
CRHR1
NCBI Official Synonym Symbols
CRF1; CRHR; CRF-R; CRFR1; CRF-R1; CRFR-1; CRH-R1; CRHR1L; CRF-R-1; CRH-R-1
UniProt Protein Name
Corticotropin-releasing factor receptor 1
UniProt Synonym Protein Names
Corticotropin-releasing hormone receptor 1; CRH-R-1; CRH-R1
Protein Family
Corticotropin-releasing factor receptor
UniProt Gene Name
CRHR1
UniProt Synonym Gene Names
CRFR; CRFR1; CRHR; CRF-R-1; CRF-R1; CRFR-1; CRH-R-1; CRH-R1
UniProt Entry Name
CRFR1_HUMAN
NCBI Protein Information
corticotropin-releasing factor receptor 1

NCBI Summary for CRHR1

This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Readthrough transcription also exists between this gene and upstream GeneID:401884 (ADP-ribosylation factor 3 pseudogene), and the readthrough transcripts encode isoforms that share similarity with the products of this gene. [provided by RefSeq, Dec 2014]
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UniProt Comments for CRHR1

CRF-R1: a G-protein coupled receptor that specifically binds corticotropin-releasing hormone, a potent mediator of endocrine, autonomic, behavioral, and immune responses to stress. Four splice-variant isoforms have been described.

Protein type: GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 17q21.31

Cellular Component: endosome; integral to membrane; integral to plasma membrane; intrinsic to plasma membrane; plasma membrane

Molecular Function: corticotrophin-releasing factor receptor activity; protein binding

Biological Process: adenylate cyclase activation; adrenocorticotropin hormone secretion; cell surface receptor linked signal transduction; female pregnancy; immune response; parturition
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Research Articles on CRHR1

1. The involvement of CRHR1 in ND.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CRHR1 elisa kit

 Reference Product  PubMed Publications
 CRH elisa kit  >193 publications with CRHR1 and CRH
 POMC elisa kit  >32 publications with CRHR1 and POMC
 CRHBP elisa kit  >21 publications with CRHR1 and CRHBP
 UCN elisa kit  >19 publications with CRHR1 and UCN
 UCN2 elisa kit  >8 publications with CRHR1 and UCN2
 CREB1 elisa kit  >2 publications with CRHR1 and CREB1
 SLC2A1 elisa kit  >1 publications with CRHR1 and SLC2A1
 DLG1 elisa kit  >1 publications with CRHR1 and DLG1
 YY1 elisa kit  >1 publications with CRHR1 and YY1

Pathways associated with CRHR1 elisa kit

 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Corticotropin-releasing Hormone Pathway antibodies  Corticotropin-releasing Hormone Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 Long-term Depression Pathway antibodies  Long-term Depression Pathway Diagram
 Long-term Depression Pathway antibodies  Long-term Depression Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Organs/Tissues associated with CRHR1 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >174 publications with CRHR1 and Brain
 Embryonic Tissue Antibodies  >5 publications with CRHR1 and Embryonic Tissue
 Ovary Antibodies  >3 publications with CRHR1 and Ovary
 Eye Antibodies  >2 publications with CRHR1 and Eye
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