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Renalase (RNLS) ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS764904

Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Mouse Rnls antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Mouse Rnls antibody was used as detection antibodies. The… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Renalase (Rnls), ELISA Kit
Full Product Name
Mouse Renalase ELISA Kit
Product Gene Name
Rnls elisa kit
Product Synonym Names
Rnls/MAO-C/chromosome 10 open reading frame 59/Monoamine oxidase-C/renalase; FAD-dependent amine oxidase
Species Reactivity
Mouse
Assay Type
Sandwich ELISA, Double Antibody
Samples
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Detection Range
31.25-2000ng/ml
Sensitivity
18.75ng/ml
Preparation and Storage
Store entire kit at 2-8C for short-term. For longer-term, please store the microplate & standard at -20C, while the remaining reagents can be stored at 2-8C
Molecular Weight
34,949 Da
OMIM
609360
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data of Rnls elisa kit

Mouse RNLS ELISA Kit – Cat# MBS764904

Typical Standard Curve of Rnls elisa kit

Mouse RNLS ELISA Kit, Typical Standard Curve – Cat# MBS764904

Other Notes

Small volumes of Rnls elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rnls purchase

MBS764904 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Renalase (Rnls) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Rnls. The ELISA analytical biochemical technique of the MBS764904 kit is based on Rnls antibody-Rnls antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Rnls antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Rnls. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for Rnls. It may not necessarily be applicable to this product.

NCBI GI #
237649117
NCBI GeneID
55328
NCBI Accession #
NP_001026879.2
UniProt Secondary Accession #
Q9BS33; Q9NUP8
UniProt Related Accession #
Q5VYX0
GenBank Nucleotide #
NM_001031709.2
NCBI Official Full Name
renalase isoform 1
NCBI Official Synonym Full Names
renalase, FAD-dependent amine oxidase
NCBI Official Symbol
RNLS
NCBI Official Synonym Symbols
C10orf59; RENALASE
UniProt Protein Name
Renalase
UniProt Synonym Protein Names
Monoamine oxidase-C; MAO-C
Protein Family
Renalase
UniProt Gene Name
RNLS
UniProt Synonym Gene Names
C10orf59; MAO-C
UniProt Entry Name
RNLS_HUMAN
NCBI Protein Information
renalase

NCBI Summary for Rnls

Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney (Xu et al., 2005 [PubMed 15841207]).[supplied by OMIM, Mar 2008]

UniProt Comments for Rnls

RENALASE: Probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. Degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. According to PubMed:17385068, is unlikely that renalase has physiologically relevant catecholamine-oxidizing activity. Belongs to the renalase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.6.3.5; Secreted, signal peptide; Oxidoreductase; Secreted

Chromosomal Location of Human Ortholog: 10q23.31

Cellular Component: extracellular space

Molecular Function: oxidoreductase activity
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Research Articles on Rnls

1. Single nucleotide polymorphisms in nNOS, renalase, MTHFR, CELSR1 and XYLB genes were found significantly associated with ischemic stroke in Chinese patients.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Rnls elisa kit

 Reference Product  PubMed Publications
 MFSD6L elisa kit  >1 publications with Rnls and MFSD6L

Diseases associated with Rnls elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >3 publications with Rnls and Inflammation
 Cardiovascular Diseases Antibodies  >2 publications with Rnls and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >2 publications with Rnls and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >2 publications with Rnls and Neoplasm Metastasis
 Hypertension Antibodies  >2 publications with Rnls and Hypertension
 Kidney Diseases Antibodies  >1 publications with Rnls and Kidney Diseases
 Heart Diseases Antibodies  >1 publications with Rnls and Heart Diseases
 Disease Models, Animal Antibodies  >1 publications with Rnls and Disease Models, Animal
 Memory Disorders Antibodies  >1 publications with Rnls and Memory Disorders
 Learning Disorders Antibodies  >1 publications with Rnls and Learning Disorders

Organs/Tissues associated with Rnls elisa kit

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >2 publications with Rnls and Eye
 Kidney Antibodies  >2 publications with Rnls and Kidney
 Muscle Antibodies  >1 publications with Rnls and Muscle
 Brain Antibodies  >1 publications with Rnls and Brain
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