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ACOT2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS766323

MBS766323 is an antibody targeting ACOT2. Also known as ACOT2 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ACOT2, Polyclonal Antibody
Full Product Name
ACOT2 Rabbit Polyclonal
Product Gene Name
anti-ACOT2 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
32,959 Da
OMIM
609972
Immunogen
Acyl-CoA thioesterase 2
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-ACOT2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Immunohistochemistry (IHC) of anti-ACOT2 antibody

Immunohistochemistry of paraffin-embedded human heart using MBS766323 (ACOT2 antibody) at dilution of 1:100
Rabbit Anti-ACOT2 Polyclonal Antibody – Cat# MBS766323

Immunofluorescence (IF) of anti-ACOT2 antibody

Immunofluorescent analysis of (10% Formaldehyde) fixed HepG2 cells using MBS766323 (ACOT2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG (H+L)
Rabbit Anti-ACOT2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS766323

Immunoprecipitation (IP) of anti-ACOT2 antibody

IP Result of anti-ACOT2 (IP: MBS766323, 3ug; Detection: MBS766323 1:500) with HepG2 cells lysate 2000ug.
Rabbit Anti-ACOT2 Polyclonal Antibody, Immunoprecipitation (IP) – Cat# MBS766323

Western Blot (WB) of anti-ACOT2 antibody

human brain tissue were subjected to SDS PAGE followed by western blot with MBS766323 (ACOT2 antibody) at dilution of 1:500
Rabbit Anti-ACOT2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS766323

Other Notes

Small volumes of anti-ACOT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ACOT2. It may not necessarily be applicable to this product.

NCBI GI #
148727286
NCBI GeneID
10965
NCBI Accession #
NP_006812.3
UniProt Secondary Accession #
Q3I5F8; Q53EK4; Q9NUX4
UniProt Related Accession #
P49753
GenBank Nucleotide #
NM_006821.5
NCBI Official Full Name
acyl-coenzyme A thioesterase 2, mitochondrial
NCBI Official Synonym Full Names
acyl-CoA thioesterase 2
NCBI Official Symbol
ACOT2
NCBI Official Synonym Symbols
MTE1; PTE2; CTE1A; PTE2A; CTE-IA; ZAP128
UniProt Protein Name
Acyl-coenzyme A thioesterase 2, mitochondrial
UniProt Synonym Protein Names
Acyl-coenzyme A thioester hydrolase 2a; CTE-Ia; Long-chain acyl-CoA thioesterase 2; ZAP128
Protein Family
Acyl-coenzyme A thioesterase
UniProt Gene Name
ACOT2
UniProt Synonym Gene Names
PTE2; PTE2A; Acyl-CoA thioesterase 2
UniProt Entry Name
ACOT2_HUMAN
NCBI Protein Information
acyl-coenzyme A thioesterase 2, mitochondrial

NCBI Summary for ACOT2

This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

UniProt Comments for ACOT2

ACOT2: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs. Belongs to the C/M/P thioester hydrolase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid Metabolism - unsaturated fatty acid biosynthesis; Hydrolase; EC 3.1.2.2; Mitochondrial

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: mitochondrial matrix; mitochondrion

Molecular Function: acyl-CoA hydrolase activity; palmitoyl-CoA hydrolase activity; receptor binding

Biological Process: acyl-CoA metabolic process; long-chain fatty acid metabolic process; very-long-chain fatty acid metabolic process
Show more

Research Articles on ACOT2

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ACOT2 antibody

 Reference Product  PubMed Publications
 UCP3 antibody  >3 publications with ACOT2 and UCP3

Pathways associated with anti-ACOT2 antibody

 Products by Pathway  Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Fatty Acyl-CoA Biosynthesis Pathway antibodies  Fatty Acyl-CoA Biosynthesis Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram

Diseases associated with anti-ACOT2 antibody

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >4 publications with ACOT2 and Fatty Liver
 Abnormalities, Drug-Induced Antibodies  >1 publications with ACOT2 and Abnormalities, Drug-Induced
 Disease Models, Animal Antibodies  >1 publications with ACOT2 and Disease Models, Animal
 Hyperplasia Antibodies  >1 publications with ACOT2 and Hyperplasia
 Weight Loss Antibodies  >1 publications with ACOT2 and Weight Loss

Organs/Tissues associated with anti-ACOT2 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >5 publications with ACOT2 and Liver
 Heart Antibodies  >5 publications with ACOT2 and Heart
 Muscle Antibodies  >4 publications with ACOT2 and Muscle
 Adrenal Gland Antibodies  >4 publications with ACOT2 and Adrenal Gland
 Blood Antibodies  >4 publications with ACOT2 and Blood
 Adipose Tissue Antibodies  >3 publications with ACOT2 and Adipose Tissue
 Connective Tissue Antibodies  >3 publications with ACOT2 and Connective Tissue
 Brain Antibodies  >2 publications with ACOT2 and Brain
 Ovary Antibodies  >1 publications with ACOT2 and Ovary
 Testis Antibodies  >1 publications with ACOT2 and Testis
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