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ASIC4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS766871

MBS766871 is an antibody targeting ASIC4. Also known as ASIC4 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ASIC4, Polyclonal Antibody
Full Product Name
ASIC4 Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
72,190 Da
OMIM
606715
Immunogen
Amiloride-sensitive cation channel 4, pituitary
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-ASIC4 antibody
ELISA (EIA), Western Blot (WB)

Western Blot (WB) of anti-ASIC4 antibody

A375 cells were subjected to SDS PAGE followed by western blot with MBS766871 (ASIC4 antibody) at dilution of 1:400
Rabbit Anti-ASIC4 Polyclonal Antibody – Cat# MBS766871

Other Notes

Small volumes of anti-ASIC4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ASIC4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
acid-sensing ion channel 4
NCBI Official Synonym Full Names
acid sensing ion channel subunit family member 4
NCBI Official Symbol
ASIC4
NCBI Official Synonym Symbols
ACCN4; BNAC4
UniProt Protein Name
Acid-sensing ion channel 4
UniProt Synonym Protein Names
Amiloride-sensitive cation channel 4; Amiloride-sensitive cation channel 4, pituitary
UniProt Gene Name
ASIC4
UniProt Synonym Gene Names
ACCN4; ASIC4
UniProt Entry Name
ASIC4_HUMAN
NCBI Protein Information
acid-sensing ion channel 4

NCBI Summary for ASIC4

This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]
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UniProt Comments for ASIC4

ASIC4: Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC4 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, sodium; Transporter; Membrane protein, integral; Transporter, ion channel; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: integral to plasma membrane

Molecular Function: ion channel activity; sodium channel activity; sodium ion transmembrane transporter activity

Biological Process: transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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