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CAPRIN2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9234424

MBS9234424 is an antibody targeting CAPRIN2. Also known as CAPRIN2 Polyclonal Antibody. Reactive in Rat, Pig. Host: Rabbit. More details

$475 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CAPRIN2, Polyclonal Antibody
Full Product Name
CAPRIN2 Polyclonal Antibody
Product Gene Name
anti-CAPRIN2 antibody
Product Synonym Names
Caprin-2; C1q domain-containing protein 1; Cytoplasmic activation/proliferation-associated protein 2; Gastric cancer multidrug resistance-associated protein; Protein EEG-1; RNA granule protein 140; CAPRIN2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat, Pig
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
OMIM
610375
3D Structure
ModBase 3D Structure for Q6IMN6
Notes
ECO:0000312|EMBL: AAI17673.1
Applications Tested/Suitable for anti-CAPRIN2 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunohistochemistry-Frozen (IHC-F), Immunofluorescence (IF), Immunocytochemistry (ICC)

Wester Blot (WB) of anti-CAPRIN2 antibody

Sample:
U87MG(Human) Cell Lysate at 30 ug
U2OS(Human) Cell Lysate at 30 ug
Primary: Anti- CAPRIN2 (bs-12423R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 126 kD
Observed band size: 126 kD
Rabbit Anti-CAPRIN2 Polyclonal Antibody – Cat# MBS9234424

Immunohistochemistry (IHC)-Paraffin of anti-CAPRIN2 antibody

Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37 degree C for 30min; Antibody incubation with (CAPRIN2) Polyclonal Antibody, Unconjugated (bs-12423R) at 1:400 overnight at 4 degree C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Rabbit Anti-CAPRIN2 Polyclonal Antibody, Immunohistochemistry (IHC)-Paraffin – Cat# MBS9234424

Flow Cytometry (FC/FACS) of anti-CAPRIN2 antibody

Dilution: Blank control: Mouse spleen cells (fixed with 2% paraformaldehyde (10 min) , then permeabilized with 90% ice-cold methanol for 30 min on ice).
Primary Antibody:Rabbit Anti-CAPRIN2 antibody(bs-12423R), Dilution: 5 µg in 100 µL 1X PBS containing 0.5% BSA;
Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions );
Secondary Antibody: Goat anti-rabbit IgG-FITC(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.
Rabbit Anti-CAPRIN2 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS9234424

Western Blot (WB) of anti-CAPRIN2 antibody

Sample:
Lane 1: U251 (Human) Cell Lysate at 30 ug
Lane 2: U87MG (Human) Cell Lysate at 30 ug
Lane 3: Huvec (Human) Cell Lysate at 30 ug
Primary: Anti-CAPRIN2 (bs-12423R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 120-140 kD
Observed band size: 140 kD
Rabbit Anti-CAPRIN2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS9234424

of anti-CAPRIN2 antibody

Paraformaldehyde-fixed, paraffin embedded (rat cerebellum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37 degree C for 30min; Antibody incubation with (CAPRIN2) Polyclonal Antibody, Unconjugated (bs-12423R) at 1:200 overnight at 4 degree C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Rabbit Anti-CAPRIN2 Polyclonal Antibody – Cat# MBS9234424

Other Notes

Small volumes of anti-CAPRIN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CAPRIN2. It may not necessarily be applicable to this product.

NCBI GI #
109734804
NCBI GeneID
65981
NCBI Accession #
AAI17674.1
UniProt Primary Accession #
Q6IMN6
UniProt Secondary Accession #
Q149P6; Q149P7; Q6IMN5; Q7Z371; Q8TE70; Q8TE71; Q96RN6; Q9H667; Q9HAL4; E4NKG2
UniProt Related Accession #
Q6IMN6
NCBI Official Full Name
CAPRIN2 protein
NCBI Official Synonym Full Names
caprin family member 2
NCBI Official Symbol
CAPRIN2
NCBI Official Synonym Symbols
EEG1; EEG-1; C1QDC1; RNG140
UniProt Protein Name
Caprin-2
UniProt Synonym Protein Names
C1q domain-containing protein 1; Cytoplasmic activation/proliferation-associated protein 2; Gastric cancer multidrug resistance-associated protein; Protein EEG-1; RNA granule protein 140
Protein Family
Caprin
UniProt Gene Name
CAPRIN2
UniProt Entry Name
CAPR2_HUMAN
NCBI Protein Information
caprin-2

NCBI Summary for CAPRIN2

The protein encoded by this gene may regulate the transport of mRNA. It may play a role in the differentiation of erythroblasts. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

UniProt Comments for CAPRIN2

C1QDC1: May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis. Belongs to the caprin family. 9 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 12p11

Cellular Component: centrosome; cytoplasm; mitochondrion; nucleus; receptor complex

Molecular Function: protein binding; receptor binding; RNA binding

Biological Process: negative regulation of cell growth; negative regulation of translation; positive regulation of dendrite morphogenesis; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein binding; positive regulation of transcription from RNA polymerase II promoter
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Research Articles on CAPRIN2

1. Caprin-2 C1q-related domain forms a flexible homotrimer mediated by calcium, and this trimeric assembly is required for the functioning of caprin-2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-CAPRIN2 antibody

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >1 publications with CAPRIN2 and Congenital Abnormalities
 Cell Transformation, Neoplastic Antibodies  >1 publications with CAPRIN2 and Cell Transformation, Neoplastic
 Liver Neoplasms Antibodies  >1 publications with CAPRIN2 and Liver Neoplasms
 Nervous System Diseases Antibodies  >1 publications with CAPRIN2 and Nervous System Diseases
 Disease Models, Animal Antibodies  >1 publications with CAPRIN2 and Disease Models, Animal
 Liver Diseases Antibodies  >1 publications with CAPRIN2 and Liver Diseases
 Necrosis Antibodies  >1 publications with CAPRIN2 and Necrosis

Organs/Tissues associated with anti-CAPRIN2 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >3 publications with CAPRIN2 and Eye
 Blood Antibodies  >2 publications with CAPRIN2 and Blood
 Skin Antibodies  >1 publications with CAPRIN2 and Skin
 Spleen Antibodies  >1 publications with CAPRIN2 and Spleen
 Muscle Antibodies  >1 publications with CAPRIN2 and Muscle
 Kidney Antibodies  >1 publications with CAPRIN2 and Kidney
 Liver Antibodies  >1 publications with CAPRIN2 and Liver
 Brain Antibodies  >1 publications with CAPRIN2 and Brain
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