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CBR4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS767558

MBS767558 is an antibody targeting CBR4. Also known as CBR4 Rabbit Polyclonal. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CBR4, Polyclonal Antibody
Full Product Name
CBR4 Rabbit Polyclonal
Product Gene Name
anti-CBR4 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
18,837 Da
Immunogen
Carbonyl reductase 4
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-CBR4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-CBR4 antibody

Immunohistochemistry of paraffin-embedded human stomach using MBS767558 (CBR4 antibody) at dilution of 1:100
Rabbit Anti-CBR4 Polyclonal Antibody – Cat# MBS767558

Western Blot (WB) of anti-CBR4 antibody

BxPC-3 cells were subjected to SDS PAGE followed by western blot with MBS767558 (CBR4 antibody) at dilution of 1:1000
Rabbit Anti-CBR4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS767558

Other Notes

Small volumes of anti-CBR4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CBR4. It may not necessarily be applicable to this product.

NCBI GI #
40254992
NCBI GeneID
84869
NCBI Accession #
NP_116172.2
UniProt Secondary Accession #
Q8WTW8; Q96K93
UniProt Related Accession #
Q8N4T8
GenBank Nucleotide #
NM_032783.4
NCBI Official Full Name
carbonyl reductase family member 4
NCBI Official Synonym Full Names
carbonyl reductase 4
NCBI Official Symbol
CBR4
NCBI Official Synonym Symbols
SDR45C1
UniProt Protein Name
Carbonyl reductase family member 4
UniProt Synonym Protein Names
3-oxoacyl-[acyl-carrier-protein] reductase (EC:1.1.1.-); Quinone reductase CBR4; Short chain dehydrogenase/reductase family 45C member 1
Protein Family
Carbonyl reductase family
UniProt Gene Name
CBR4
UniProt Synonym Gene Names
SDR45C1
UniProt Entry Name
CBR4_HUMAN
NCBI Protein Information
carbonyl reductase family member 4

UniProt Comments for CBR4

CBR4: The heteroteramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro). Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Oxidoreductase; EC 1.-.-.-; EC 1.1.1.-

Chromosomal Location of Human Ortholog: 4q32.3

Cellular Component: mitochondrial matrix

Molecular Function: NAD(P)H dehydrogenase (quinone) activity; NADPH dehydrogenase (quinone) activity; protein binding; quinone binding

Biological Process: fatty acid biosynthetic process; protein homotetramerization
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Research Articles on CBR4

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CBR4 antibody

 Reference Product  PubMed Publications
 CBR3 antibody  >6 publications with CBR4 and CBR3
 CBR1 antibody  >2 publications with CBR4 and CBR1

Diseases associated with anti-CBR4 antibody

 Disease Name  Pubmed Publications
 Vascular Diseases Antibodies  >1 publications with CBR4 and Vascular Diseases
 Fibrosis Antibodies  >1 publications with CBR4 and Fibrosis

Organs/Tissues associated with anti-CBR4 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >4 publications with CBR4 and Liver
 Kidney Antibodies  >2 publications with CBR4 and Kidney
 Muscle Antibodies  >1 publications with CBR4 and Muscle
 Blood Antibodies  >1 publications with CBR4 and Blood
 Vascular Antibodies  >1 publications with CBR4 and Vascular
 Uterus Antibodies  >1 publications with CBR4 and Uterus
 Prostate Antibodies  >1 publications with CBR4 and Prostate
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