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Cytokeratin 14 (KRT14) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS768429

MBS768429 is an antibody targeting KRT14. Also known as Cytokeratin 14 Mouse Monoclonal. Reactive in Human, Mouse. Host: Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cytokeratin 14 (KRT14), Monoclonal Antibody
Full Product Name
Cytokeratin 14 Mouse Monoclonal
Product Gene Name
anti-KRT14 antibody
Clonality
Monoclonal
Isotype
IgG2a
Host
Mouse
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Protein A+G purification
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
51,561 Da
OMIM
125595
3D Structure
ModBase 3D Structure for P02533
Immunogen
Keratin 14
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-KRT14 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

Immunohistochemistry (IHC) of anti-KRT14 antibody

Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using MBS768429 (Cytokeratin 14 antibody) at dilution of 1:400. heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .
Mouse Anti-KRT14 Monoclonal Antibody – Cat# MBS768429

Western Blot (WB) of anti-KRT14 antibody

A431 cells were subjected to SDS PAGE followed by western blot with MBS768429 (Cytokeratin 14) antibody at dilution of 1:500
Mouse Anti-KRT14 Monoclonal Antibody, Western Blot (WB) – Cat# MBS768429

Other Notes

Small volumes of anti-KRT14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KRT14. It may not necessarily be applicable to this product.

NCBI GI #
355568680
NCBI Accession #
EHH24961.1
UniProt Primary Accession #
P02533
UniProt Secondary Accession #
Q14715; Q53XY3; Q9BUE3; Q9UBN2; Q9UBN3; Q9UCY4
NCBI Official Full Name
Cytokeratin-14
UniProt Protein Name
Keratin, type I cytoskeletal 14
UniProt Synonym Protein Names
Cytokeratin-14; CK-14; Keratin-14; K14
Protein Family
Keratin
UniProt Gene Name
KRT14
UniProt Synonym Gene Names
CK-14; K14
UniProt Entry Name
K1C14_HUMAN

UniProt Comments for KRT14

K14: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Generally associates with K5.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: cytoplasm; cytosol; intermediate filament; keratin filament; nucleus

Molecular Function: protein binding; structural constituent of cytoskeleton

Biological Process: aging; epidermis development; epithelial cell differentiation; hair cycle; hemidesmosome assembly; intermediate filament bundle assembly; response to ionizing radiation; response to zinc ion

Disease: Dermatopathia Pigmentosa Reticularis; Epidermolysis Bullosa Simplex, Autosomal Recessive 1; Epidermolysis Bullosa Simplex, Dowling-meara Type; Epidermolysis Bullosa Simplex, Generalized; Epidermolysis Bullosa Simplex, Localized; Naegeli Syndrome
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KRT14 antibody

 Reference Product  PubMed Publications
 KRT5 antibody  >109 publications with KRT14 and KRT5
 DST antibody  >4 publications with KRT14 and DST
 IVL antibody  >1 publications with KRT14 and IVL
 CREBBP antibody  >1 publications with KRT14 and CREBBP
 KRT3 antibody  >1 publications with KRT14 and KRT3

Diseases associated with anti-KRT14 antibody

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >103 publications with KRT14 and Congenital Abnormalities
 Epidermolysis Bullosa Simplex Antibodies  >98 publications with KRT14 and Epidermolysis Bullosa Simplex
 Carcinoma Antibodies  >61 publications with KRT14 and Carcinoma
 Carcinoma, Squamous Cell Antibodies  >39 publications with KRT14 and Carcinoma, Squamous Cell
 Hyperplasia Antibodies  >21 publications with KRT14 and Hyperplasia
 Breast Neoplasms Antibodies  >18 publications with KRT14 and Breast Neoplasms
 Inflammation Antibodies  >14 publications with KRT14 and Inflammation
 Necrosis Antibodies  >13 publications with KRT14 and Necrosis
 Cell Transformation, Neoplastic Antibodies  >13 publications with KRT14 and Cell Transformation, Neoplastic
 Pigmentation Disorders Antibodies  >10 publications with KRT14 and Pigmentation Disorders

Organs/Tissues associated with anti-KRT14 antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >170 publications with KRT14 and Skin
 Blood Antibodies  >25 publications with KRT14 and Blood
 Mouth Antibodies  >16 publications with KRT14 and Mouth
 Lung Antibodies  >10 publications with KRT14 and Lung
 Eye Antibodies  >9 publications with KRT14 and Eye
 Mammary Gland Antibodies  >8 publications with KRT14 and Mammary Gland
 Esophagus Antibodies  >8 publications with KRT14 and Esophagus
 Liver Antibodies  >7 publications with KRT14 and Liver
 Bladder Antibodies  >6 publications with KRT14 and Bladder
 Connective Tissue Antibodies  >6 publications with KRT14 and Connective Tissue
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