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GTPBP4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS769954

MBS769954 is an antibody targeting GTPBP4. Also known as GTPBP4 Rabbit Polyclonal. Reactive in Human, Mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GTPBP4, Polyclonal Antibody
Full Product Name
GTPBP4 Rabbit Polyclonal
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
60,051 Da
Immunogen
GTP binding protein 4
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-GTPBP4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Immunohistochemistry (IHC) of anti-GTPBP4 antibody

Immunohistochemistry of paraffin-embedded human cervical cancer using MBS769954 (GTPBP4 antibody) at dilution of 1:100
Rabbit Anti-GTPBP4 Polyclonal Antibody – Cat# MBS769954

Western Blot (WB) of anti-GTPBP4 antibody

mouse testis tissue were subjected to SDS PAGE followed by western blot with MBS769954 (GTPBP4 antibody) at dilution of 1:800
Rabbit Anti-GTPBP4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS769954

Other Notes

Small volumes of anti-GTPBP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GTPBP4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
GTPBP4 protein, partial
NCBI Official Synonym Full Names
GTP binding protein 4
NCBI Official Symbol
GTPBP4
NCBI Official Synonym Symbols
NGB; CRFG; NOG1
UniProt Protein Name
Nucleolar GTP-binding protein 1
UniProt Synonym Protein Names
Chronic renal failure gene protein; GTP-binding protein NGB
UniProt Gene Name
GTPBP4
UniProt Synonym Gene Names
CRFG; NOG1
UniProt Entry Name
NOG1_HUMAN
NCBI Protein Information
nucleolar GTP-binding protein 1

NCBI Summary for GTPBP4

GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008]
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UniProt Comments for GTPBP4

GTPBP4: Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the GTP1/OBG family. NOG subfamily.

Protein type: RNA-binding; Nucleolus; Ribosomal

Chromosomal Location of Human Ortholog: 10p15-p14

Cellular Component: cytoplasm; Golgi apparatus; membrane; nuclear membrane; nucleolus; nucleus; perinuclear region of cytoplasm

Molecular Function: GTP binding; GTPase activity; protein binding

Biological Process: negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of cell-cell adhesion; negative regulation of collagen binding; negative regulation of DNA replication; negative regulation of protein ubiquitination; osteoblast differentiation; protein stabilization; regulation of cyclin-dependent protein kinase activity; ribosome biogenesis and assembly
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-GTPBP4 antibody

Organs/Tissues associated with anti-GTPBP4 antibody

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