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Beclin 2 (BECN2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS809398

Beclin 2 is a novel coiled-coil protein related to the autophagic Beclin 1 protein. It is thought to interact with Bcl-2, an anti-apoptotic protein, and is believed to function in autophagy. It has alson been found to mediate G protein-coupled receptro (GPCR)… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
Beclin 2 (BECN2), Polyclonal Antibody
Full Product Name
Beclin 2 Antibody: RPE
Product Gene Name
Product Synonym Names
Rabbit Anti-Human Beclin 2 Polyclonal; BECN1P1 Antibody; Beclin-1 autophagy-related pseudogene 1 Antibody; BECN2 Antibody; Beclin-2 Antibody; BECN1L1 Antibody; Beclin-1-like protein 1 Antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human; Rat
Purity/Purification
Peptide Affinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Detects ~48 kDa.
Preparation and Storage
Store at -20 degree C.
Molecular Weight
48,153 Da
OMIM
615687
3D Structure
ModBase 3D Structure for A8MW95
Target
Beclin 2
Immunogen
Synthetic peptide from the C-terminal of Human Beclin 2 (aa. 338-349)
Immunogen Species
Human
Cellular Localization
Cytoplasm
Conjugate
RPE
Storage Buffer
PBS, 50% glycerol, 0.09% sodium azide
Tissue Specificity
Present in fetal and adult brain (at protein level).
Applications Tested/Suitable for anti-BECN2 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-BECN2 antibody
WB: 1:1000
ICC/IF: 1:100

Western Blot (WB) of anti-BECN2 antibody

Western blot analysis of Rat Liver cell lysates showing detection of 48.1 kDa Beclin 2 protein using Rabbit Anti-Beclin 2 Polyclonal Antibody (SPC-603). Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Liver cell lysates. Load: 15 ug. Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-Beclin 2 Polyclonal Antibody (SPC-603) at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Rabbit HRP at 1:2000 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: 48.1 kDa.
Rabbit Anti-BECN2 Polyclonal Antibody – Cat# MBS809398

Product References and Citations for anti-BECN2 antibody

1. He C., et al. (2013) Cell. 154(5): 1085-1099.

Other Notes

Small volumes of anti-BECN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BECN2 purchase

MBS809398 is an antibody targeting BECN2. Also known as Beclin 2 Antibody: RPE. Reactive in Human; Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BECN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
beclin-2
NCBI Official Synonym Full Names
beclin 2
NCBI Official Symbol
BECN2
NCBI Official Synonym Symbols
BECN1L1; BECN1P1
UniProt Protein Name
Beclin-2
UniProt Synonym Protein Names
Beclin-1 autophagy-related pseudogene 1
Protein Family
UniProt Gene Name
BECN2
NCBI Protein Information
beclin-2

UniProt Comments for BECN2

Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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