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DNAJB11 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821509

MBS821509 is an antibody targeting DNAJB11. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to DNAJB11 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DNAJB11, Polyclonal Antibody
Full Product Name
Anti-DNAJB11 Antibody
Product Gene Name
anti-DNAJB11 antibody
Product Synonym Names
EDJ; ERJ3; HDJ9; DnaJ homolog subfamily B member 11; APOBEC1-binding protein 2; ABBP-2; DnaJ protein homolog 9; ER-associated DNAJ; ER-associated Hsp40 co-chaperone; Endoplasmic reticulum DNA J domain-containing protein 3; ER-resident protein ERdj3; ERdj3; ERj3p; HEDJ; Human DnaJ protein 9; hDj-9; PWP1-interacting protein 4
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of DNAJB11 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
DNAJB11 peptide (MBS822726) is used for blocking the activity of DNAJB11 antibody (MBS821509)
Molecular Weight
40,514 Da
OMIM
611341
3D Structure
ModBase 3D Structure for Q9UBS4
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DNAJB11. The exact sequence is proprietary.
Applications Tested/Suitable for anti-DNAJB11 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Application Notes for anti-DNAJB11 antibody
WB (1/500 - 1/1000), IH (1/100 - 1/200), IP (1/10 - 1/100)

Western Blot (WB) of anti-DNAJB11 antibody

Western blot analysis of DNAJB11 expression in HuvEc (A), NCIH460 (B), MCF7 (C) whole cell lysates.
Rabbit Anti-DNAJB11 Polyclonal Antibody – Cat# MBS821509

Immunohistochemistry (IHC) of anti-DNAJB11 antibody

Immunohistochemical analysis of DNAJB11 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-DNAJB11 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS821509

Other Notes

Small volumes of anti-DNAJB11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DNAJB11. It may not necessarily be applicable to this product.

NCBI GI #
7706495
NCBI GeneID
51726
NCBI Accession #
NP_057390.1
UniProt Primary Accession #
Q9UBS4
UniProt Secondary Accession #
Q542Y5; Q542Y9; Q6IAQ8; Q96JC6
UniProt Related Accession #
Q9UBS4
GenBank Nucleotide #
NM_016306.5
NCBI Official Full Name
dnaJ homolog subfamily B member 11
NCBI Official Synonym Full Names
DnaJ (Hsp40) homolog, subfamily B, member 11
NCBI Official Symbol
DNAJB11
NCBI Official Synonym Symbols
DJ9; EDJ; Dj-9; ERj3; ABBP2; ERdj3; ERj3p; ABBP-2; UNQ537; PRO1080
UniProt Protein Name
DnaJ homolog subfamily B member 11
UniProt Synonym Protein Names
APOBEC1-binding protein 2; ABBP-2; DnaJ protein homolog 9; ER-associated DNAJ; ER-associated Hsp40 co-chaperone; Endoplasmic reticulum DNA J domain-containing protein 3; ER-resident protein ERdj3; ERdj3; ERj3p; HEDJ; Human DnaJ protein 9; hDj-9; PWP1-interacting protein 4
Protein Family
DnaJ homolog subfamily
UniProt Gene Name
DNAJB11
UniProt Synonym Gene Names
EDJ; ERJ3; HDJ9; ABBP-2; ER-resident protein ERdj3; ERdj3; ERj3p; hDj-9
UniProt Entry Name
DJB11_HUMAN
NCBI Protein Information
dnaJ homolog subfamily B member 11; DnaJ protein 9; APOBEC1-binding protein 2; ER-resident protein ERdj3; PWP1-interacting protein 4; ER-associated DNAJ protein 3; ER-associated Hsp40 co-chaperone; endoplasmic reticulum DNA J domain-containing protein 3

NCBI Summary for DNAJB11

This gene encodes a soluble glycoprotein of the endoplasmic reticulum (ER) lumen that functions as a co-chaperone of binding immunoglobulin protein, a 70 kilodalton heat shock protein chaperone required for the proper folding and assembly of proteins in the ER. The encoded protein contains a highly conserved J domain of about 70 amino acids with a characteristic His-Pro-Asp (HPD) motif and may regulate the activity of binding immunoglobulin protein by stimulating ATPase activity. [provided by RefSeq, Mar 2014]
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UniProt Comments for DNAJB11

DNAJB11: Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.

Protein type: Secreted, signal peptide; Chaperone; Endoplasmic reticulum; RNA processing; Secreted

Chromosomal Location of Human Ortholog: 3q27.3

Cellular Component: membrane; endoplasmic reticulum lumen; endoplasmic reticulum; nucleus

Molecular Function: protein binding; unfolded protein binding

Biological Process: cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; protein folding; unfolded protein response; mRNA modification
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Research Articles on DNAJB11

1. ERdjs appear to play the dual roles of increasing BiP affinity for clients and regulating delivery of clients to BiP.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DNAJB11 antibody

 Reference Product  PubMed Publications
 SDF2L1 antibody  >1 publications with DNAJB11 and SDF2L1

Pathways associated with anti-DNAJB11 antibody

 Products by Pathway  Pathway Diagram
 IRE1alpha Activates Chaperones Pathway antibodies  IRE1alpha Activates Chaperones Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Unfolded Protein Response (UPR) Pathway antibodies  Unfolded Protein Response (UPR) Pathway Diagram
 XBP1(S) Activates Chaperone Genes Pathway antibodies  XBP1(S) Activates Chaperone Genes Pathway Diagram

Diseases associated with anti-DNAJB11 antibody

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >1 publications with DNAJB11 and Adenocarcinoma

Organs/Tissues associated with anti-DNAJB11 antibody

 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >3 publications with DNAJB11 and Pancreas
 Kidney Antibodies  >1 publications with DNAJB11 and Kidney
 Muscle Antibodies  >1 publications with DNAJB11 and Muscle
 Stomach Antibodies  >1 publications with DNAJB11 and Stomach
 Placenta Antibodies  >1 publications with DNAJB11 and Placenta
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