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UBE4A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821668

MBS821668 is an antibody targeting UBE4A. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to UBE4A More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UBE4A, Polyclonal Antibody
Full Product Name
Anti-UBE4A Antibody
Product Gene Name
Product Synonym Names
KIAA0126; Ubiquitin conjugation factor E4 A
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of UBE4A protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
UBE4A peptide (MBS822410) is used for blocking the activity of UBE4A antibody (MBS821668)
Molecular Weight
123,522 Da
OMIM
603753
3D Structure
ModBase 3D Structure for Q14139
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human UBE4A. The exact sequence is proprietary.
Applications Tested/Suitable for anti-UBE4A antibody
Western Blot (WB)
Application Notes for anti-UBE4A antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-UBE4A antibody

Western blot analysis of UBE4A expression in HepG2 (A), SP2/0 (B), H9C2 (C) whole cell lysates.
Rabbit Anti-UBE4A Polyclonal Antibody – Cat# MBS821668

Other Notes

Small volumes of anti-UBE4A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UBE4A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ubiquitin conjugation factor E4 A isoform 2
NCBI Official Synonym Full Names
ubiquitination factor E4A
NCBI Official Symbol
UBE4A
NCBI Official Synonym Symbols
E4; UFD2; UBOX2
UniProt Protein Name
Ubiquitin conjugation factor E4 A
UniProt Gene Name
UBE4A
UniProt Entry Name
UBE4A_HUMAN
NCBI Protein Information
ubiquitin conjugation factor E4 A; ubiquitination factor E4A (UFD2 homolog, yeast)

NCBI Summary for UBE4A

This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
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UniProt Comments for UBE4A

UBE4A: Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3. Belongs to the ubiquitin conjugation factor E4 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.3.2.19; Ligase; Ubiquitin ligase; EC 6.3.2.-; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: cytoplasm; ubiquitin ligase complex

Molecular Function: protein binding; ligase activity

Biological Process: ubiquitin-dependent protein catabolic process; protein polyubiquitination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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