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Tetraspanin 8 (TSPAN8) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS821795

MBS821795 is an antibody targeting TSPAN8. Also known as Anti-Tetraspanin 8 Antibody. Reactive in Human. Host: Rabbit. Rabbit polyclonal antibody to Tetraspanin 8 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tetraspanin 8 (TSPAN8), Polyclonal Antibody
Full Product Name
Anti-Tetraspanin 8 Antibody
Product Gene Name
Product Synonym Names
TM4SF3; Tetraspanin-8; Tspan-8; Transmembrane 4 superfamily member 3; Tumor-associated antigen CO-029
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of Tetraspanin 8 protein.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
OMIM
600769
3D Structure
ModBase 3D Structure for P19075
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Tetraspanin 8. The exact sequence is proprietary.
Applications Tested/Suitable for anti-TSPAN8 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TSPAN8 antibody
WB (1/500 - 1/1000), IH (1/100 - 1/200)

Western Blot (WB) of anti-TSPAN8 antibody

Western blot analysis of Tetraspanin 8 expression in HEK293T (A), Hela (B), HGC27 (C), mouse testis (D), rat testis (E) whole cell lysates.
Rabbit Anti-TSPAN8 Polyclonal Antibody – Cat# MBS821795

Immunohistochemistry (IHC) of anti-TSPAN8 antibody

Immunohistochemical analysis of Tetraspanin 8 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-TSPAN8 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS821795

Other Notes

Small volumes of anti-TSPAN8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TSPAN8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tetraspanin-8
NCBI Official Synonym Full Names
tetraspanin 8
NCBI Official Symbol
TSPAN8
NCBI Official Synonym Symbols
CO-029; TM4SF3
UniProt Protein Name
Tetraspanin-8
UniProt Synonym Protein Names
Transmembrane 4 superfamily member 3; Tumor-associated antigen CO-029
Protein Family
UniProt Gene Name
TSPAN8
UniProt Synonym Gene Names
TM4SF3; Tspan-8
UniProt Entry Name
TSN8_HUMAN
NCBI Protein Information
tetraspanin-8; tspan-8; tumor-associated antigen CO-029; transmembrane 4 superfamily member 3

NCBI Summary for TSPAN8

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for TSPAN8

TSPAN8: is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q14.1-q21.1

Cellular Component: integral to membrane

Biological Process: negative regulation of blood coagulation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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