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Tetraspanin

Below are the list of possible Tetraspanin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the reer's specifications.

Tetraspanin-18

Also known as Tetraspanin-18 (TOM2A homologous protein 2).
May be involved in the regulation of cell differentiation.

Tetraspanin-19

Also known as Tetraspanin-19 (TOM2A homologous protein 3).
May be involved in the regulation of cell differentiation.

Tetraspanin-20

Also known as Tetraspanin-20 (TOM2A homologous protein 1).
May be involved in the regulation of cell differentiation.

Tetraspanin-2A

Required for assembly of smooth septate junctions (sSJs), together with Ssk and mesh. Important for barrier function of the midgut epithelium.

Tetraspanin-32

Also known as Tetraspanin-32 (Tspan-32) (AML1-regulated transmembrane protein 1) (Protein Phemx).
TSPAN32: This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: cell surface; intracellular

Biological Process: blood coagulation; cytoskeleton organization and biogenesis; defense response to protozoan; hemostasis; integrin-mediated signaling pathway; negative regulation of cell proliferation; negative regulation of myeloid dendritic cell activation; regulation of defense response to virus

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