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Adenylate Cyclase 9 (ADCY9) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS822184

MBS822184 is an antibody targeting ADCY9. Also known as Anti-Adenylate Cyclase 9 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. Rabbit polyclonal antibody to Adenylate Cyclase 9 More details

$225 / 0.03 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Adenylate Cyclase 9 (ADCY9), Polyclonal Antibody
Full Product Name
Anti-Adenylate Cyclase 9 Antibody
Product Gene Name
anti-ADCY9 antibody
Product Synonym Names
KIAA0520; Adenylate cyclase type 9; ATP pyrophosphate-lyase 9; Adenylate cyclase type IX; Adenylyl cyclase 9
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of Adenylate Cyclase 9 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
Adenylate Cyclase 9 peptide (MBS824183) is used for blocking the activity of Adenylate Cyclase 9 antibody (MBS822184)
Molecular Weight
150,701 Da
OMIM
603302
3D Structure
ModBase 3D Structure for O60503
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Adenylate Cyclase 9. The exact sequence is proprietary.
Applications Tested/Suitable for anti-ADCY9 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-ADCY9 antibody
WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/ICC (1/100 - 1/500)

Western Blot (WB) of anti-ADCY9 antibody

Western blot analysis of Adenylate Cyclase 9 expression in HeLa (A), SP2/0 (B), H9C2 (C) whole cell lysates.
Rabbit Anti-ADCY9 Polyclonal Antibody – Cat# MBS822184

Immunohistochemistry (IHC) of anti-ADCY9 antibody

Immunohistochemical analysis of Adenylate Cyclase 9 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-ADCY9 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS822184

Immunofluorescence (IF) of anti-ADCY9 antibody

Immunofluorescent analysis of Adenylate Cyclase 9 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Rabbit Anti-ADCY9 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS822184

Other Notes

Small volumes of anti-ADCY9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ADCY9. It may not necessarily be applicable to this product.

NCBI GI #
50959205
NCBI GeneID
115
NCBI Accession #
NP_001107.2
UniProt Primary Accession #
O60503
UniProt Secondary Accession #
O60273; Q4ZHT9; Q4ZIR5; Q9BWT4; Q9UGP2; A7E2V5; A7E2X2; D3DUD1
UniProt Related Accession #
O60503
GenBank Nucleotide #
NM_001116.3
NCBI Official Full Name
adenylate cyclase type 9
NCBI Official Synonym Full Names
adenylate cyclase 9
NCBI Official Symbol
ADCY9
NCBI Official Synonym Symbols
AC9
UniProt Protein Name
Adenylate cyclase type 9
UniProt Synonym Protein Names
ATP pyrophosphate-lyase 9; Adenylate cyclase type IX; Adenylyl cyclase 9
Protein Family
Adenylate cyclase
UniProt Gene Name
ADCY9
UniProt Synonym Gene Names
KIAA0520
UniProt Entry Name
ADCY9_HUMAN
NCBI Protein Information
adenylate cyclase type 9; adenylyl cyclase 9; ATP pyrophosphate-lyase 9; adenylate cyclase type IX; type IX ATP pyrophosphate-lyase

NCBI Summary for ADCY9

Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008]
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UniProt Comments for ADCY9

ADCY9: May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Protein type: Membrane protein, integral; Nucleotide Metabolism - purine; Transporter; Adenylyl cyclase; Membrane protein, multi-pass; Transporter, aquaporin family; Lyase; EC 4.6.1.1

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: metal ion binding; ATP binding; adenylate cyclase activity

Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; water transport; activation of protein kinase A; signal transduction; G-protein signaling, adenylate cyclase activating pathway; synaptic transmission; phospholipase C activation; energy reserve metabolic process; renal water homeostasis; innate immune response; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; transmembrane transport
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Research Articles on ADCY9

1. Data indicate that adenylyl cyclase 9 (AC9) transcript is a direct target of miR-181b.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ADCY9 antibody

 Reference Product  PubMed Publications
 ADCY8 antibody  >2 publications with ADCY9 and ADCY8
 ADRB2 antibody  >2 publications with ADCY9 and ADRB2
 PDE7A antibody  >1 publications with ADCY9 and PDE7A
 PDE4D antibody  >1 publications with ADCY9 and PDE4D
 PDE8A antibody  >1 publications with ADCY9 and PDE8A
 PDE4A antibody  >1 publications with ADCY9 and PDE4A

Pathways associated with anti-ADCY9 antibody

 Products by Pathway  Pathway Diagram
 Activation Of GABAB Receptors Pathway antibodies  Activation Of GABAB Receptors Pathway Diagram
 Adenylate Cyclase Activating Pathway antibodies  Adenylate Cyclase Activating Pathway Diagram
 Adenylate Cyclase Inhibitory Pathway antibodies  Adenylate Cyclase Inhibitory Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Ca-dependent Events Pathway antibodies  Ca-dependent Events Pathway Diagram
 CaM Pathway antibodies  CaM Pathway Diagram

Diseases associated with anti-ADCY9 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3 publications with ADCY9 and Nervous System Diseases
 Adenocarcinoma Antibodies  >2 publications with ADCY9 and Adenocarcinoma
 Brain Diseases Antibodies  >2 publications with ADCY9 and Brain Diseases
 Neurobehavioral Manifestations Antibodies  >2 publications with ADCY9 and Neurobehavioral Manifestations
 Neoplasm Metastasis Antibodies  >1 publications with ADCY9 and Neoplasm Metastasis
 Disease Models, Animal Antibodies  >1 publications with ADCY9 and Disease Models, Animal
 Liver Neoplasms, Experimental Antibodies  >1 publications with ADCY9 and Liver Neoplasms, Experimental
 Depressive Disorder Antibodies  >1 publications with ADCY9 and Depressive Disorder
 Cardiovascular Diseases Antibodies  >1 publications with ADCY9 and Cardiovascular Diseases
 Liver Diseases Antibodies  >1 publications with ADCY9 and Liver Diseases

Organs/Tissues associated with anti-ADCY9 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with ADCY9 and Brain
 Nerve Antibodies  >2 publications with ADCY9 and Nerve
 Prostate Antibodies  >1 publications with ADCY9 and Prostate
 Testis Antibodies  >1 publications with ADCY9 and Testis
 Kidney Antibodies  >1 publications with ADCY9 and Kidney
 Eye Antibodies  >1 publications with ADCY9 and Eye
 Liver Antibodies  >1 publications with ADCY9 and Liver
 Ovary Antibodies  >1 publications with ADCY9 and Ovary
 Muscle Antibodies  >1 publications with ADCY9 and Muscle
 Lung Antibodies  >1 publications with ADCY9 and Lung
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