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Cd120b (TNFRSF1B) ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS824562

Sandwich ELISA for quantitative detection of Mouse CD120b concentrations. More details

$640 / 96 Tests +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD120b (TNFRSF1B), ELISA Kit
Full Product Name
Mouse CD120b ELISA Kit
Product Gene Name
TNFRSF1B elisa kit
Product Synonym Names
TNFBR; TNFR2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; TNF-RII; TNFR-II; p75; p80 TNF-alpha receptor; CD120b; Etanercept
Species Reactivity
Mouse
Assay Type
Sandwich
Samples
Cell Culture Supernatants, Serum
Detection Range
15.6 pg/ml - 1000 pg/ml
Sensitivity
1 pg/ml
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
50,320 Da
3D Structure
ModBase 3D Structure for P25119
Detection Method
Colorimetric
Applications Tested/Suitable for TNFRSF1B elisa kit
Sandwich ELISA (SE)

Typical Testing Data/Standard Curve (for reference only) of TNFRSF1B elisa kit

Mouse TNFRSF1B ELISA Kit – Cat# MBS824562

Other Notes

Small volumes of TNFRSF1B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TNFRSF1B purchase

MBS824562 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CD120b (TNFRSF1B) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TNFRSF1B. The ELISA analytical biochemical technique of the MBS824562 kit is based on TNFRSF1B antibody-TNFRSF1B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TNFRSF1B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TNFRSF1B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for TNFRSF1B. It may not necessarily be applicable to this product.

NCBI GI #
70778792
NCBI GeneID
21938
NCBI Accession #
NP_035740.2
UniProt Primary Accession #
P25119
UniProt Secondary Accession #
O88734; P97893
UniProt Related Accession #
P25119
GenBank Nucleotide #
NM_011610.3
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 1B
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 1b
NCBI Official Symbol
Tnfrsf1b
NCBI Official Synonym Symbols
p75; TNFBR; Tnfr2; CD120b; TNF-R2; TNFR80; TNFRII; Tnfr-1; TNF-R75; TNF-R-II; TNF-alphaR2; TNFalpha-R2
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 1B
UniProt Synonym Protein Names
Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; TNF-RII; TNFR-II; p75; p80 TNF-alpha receptor; CD_antigen: CD120b
Protein Family
Tumor necrosis factor receptor superfamily
UniProt Gene Name
Tnfrsf1b
UniProt Synonym Gene Names
Tnfr-2; Tnfr2; TNF-R2; TNF-RII; TNFR-II
UniProt Entry Name
TNR1B_MOUSE
NCBI Protein Information
tumor necrosis factor receptor superfamily member 1B; TNF-RII; TNFR-II; p75 TNFR; p80 TNF-alpha receptor; TNF receptor beta chain; tumor necrosis factor receptor 2; tumor necrosis factor receptor type II

UniProt Comments for TNFRSF1B

TNF-R2: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. Binds to TRAF2. Interacts with BMX. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, cytokine

Cellular Component: cell soma; membrane; perinuclear region of cytoplasm; axon; integral to membrane; intracellular; nucleus; lipid raft

Molecular Function: protein binding; tumor necrosis factor receptor activity; ubiquitin protein ligase binding

Biological Process: cell proliferation; cell surface receptor linked signal transduction; DNA damage response, signal transduction resulting in induction of apoptosis; tumor necrosis factor-mediated signaling pathway; negative regulation of inflammatory response; programmed cell death; immune response; RNA destabilization; inflammatory response; positive regulation of membrane protein ectodomain proteolysis
Show more

Research Articles on TNFRSF1B

1. TNFR2 signaling by itself is both sufficient and required to induce Vbeta5+ Treg expansion.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TNFRSF1B elisa kit

 Products by Pathway  Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 IL-3 Signaling Pathway antibodies  IL-3 Signaling Pathway Diagram
 Inflammatory Response Pathway antibodies  Inflammatory Response Pathway Diagram
 Oxidative Damage Pathway antibodies  Oxidative Damage Pathway Diagram

Diseases associated with TNFRSF1B elisa kit

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >127 publications with TNFRSF1B and Necrosis
 Inflammation Antibodies  >37 publications with TNFRSF1B and Inflammation
 Cardiovascular Diseases Antibodies  >15 publications with TNFRSF1B and Cardiovascular Diseases
 Lung Diseases Antibodies  >12 publications with TNFRSF1B and Lung Diseases
 Heart Diseases Antibodies  >10 publications with TNFRSF1B and Heart Diseases
 Carcinoma Antibodies  >9 publications with TNFRSF1B and Carcinoma
 Obesity Antibodies  >9 publications with TNFRSF1B and Obesity
 Nervous System Diseases Antibodies  >8 publications with TNFRSF1B and Nervous System Diseases
 Hypertension Antibodies  >8 publications with TNFRSF1B and Hypertension
 Kidney Diseases Antibodies  >5 publications with TNFRSF1B and Kidney Diseases

Organs/Tissues associated with TNFRSF1B elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >64 publications with TNFRSF1B and Blood
 Bone Antibodies  >14 publications with TNFRSF1B and Bone
 Lung Antibodies  >8 publications with TNFRSF1B and Lung
 Kidney Antibodies  >7 publications with TNFRSF1B and Kidney
 Liver Antibodies  >5 publications with TNFRSF1B and Liver
 Skin Antibodies  >5 publications with TNFRSF1B and Skin
 Bone Marrow Antibodies  >5 publications with TNFRSF1B and Bone Marrow
 Joint Antibodies  >4 publications with TNFRSF1B and Joint
 Connective Tissue Antibodies  >4 publications with TNFRSF1B and Connective Tissue
 Eye Antibodies  >3 publications with TNFRSF1B and Eye
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