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Il-28ra Blocking Peptide – >85% Purity

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS822916

MBS822916 is a blocking peptide targeting IL28RA. Also known as IL-28RA Blocking Peptide. Reactive in Human. The peptide is used to block Anti-IL-28RA Antibody reactivity. More details

$230 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL-28RA (IL28RA), Blocking Peptide
Full Product Name
IL-28RA Blocking Peptide
Product Gene Name
Product Synonym Names
IL28RA; LICR2; Interferon lambda receptor 1; IFN-lambda receptor 1; IFN-lambda-R1; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; CRF2-12; Interleukin-28 receptor subunit alpha; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; Likely interleukin or cytokine receptor 2; LICR2
Species Reactivity
Human
Form/Format
Lyophilized powder
Purity/Purification
>85%
Preparation and Storage
Store at -20°C for one year.
Antibody/Peptide Pairs
IL-28RA peptide (MBS822916) is used for blocking the activity of IL-28RA antibody (MBS820358)
OMIM
607404
Source
Synthetic
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Applications Tested/Suitable for IL28RA blocking peptide
Blocking (BL)
Application Notes for IL28RA blocking peptide
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4°C for overnight or at room temperature for 2 hours.

Other Notes

Small volumes of IL28RA blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL28RA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interferon lambda receptor 1 isoform 1
NCBI Official Synonym Full Names
interferon, lambda receptor 1
NCBI Official Symbol
IFNLR1
NCBI Official Synonym Symbols
IFNLR; LICR2; IL28RA; CRF2/12; IL-28R1
UniProt Protein Name
Interferon lambda receptor 1
UniProt Synonym Protein Names
Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; CRF2-12; Interleukin-28 receptor subunit alpha; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; Likely interleukin or cytokine receptor 2; LICR2
UniProt Gene Name
IFNLR1
UniProt Synonym Gene Names
IL28RA; LICR2; IFN-lambda receptor 1; IFN-lambda-R1; CRF2-12; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; LICR2
UniProt Entry Name
INLR1_HUMAN
NCBI Protein Information
interferon lambda receptor 1; CRF2-12; IL-28RA; IL-28R-alpha; IFN-lambda-R1; IFN-lambda receptor 1; interleukin 28 receptor A; IL-28 receptor subunit alpha; interferon lambda, receptor 1; interleukin 28 alpha receptor; class II cytokine receptor CRF2/12; interleukin or cytokine receptor 2; cytokine receptor class-II member 12; cytokine receptor family 2 member 12; interleukin-28 receptor subunit alpha; likely interleukin or cytokine receptor 2; interleukin 28 receptor, alpha (interferon, lambda receptor)

NCBI Summary for IL28RA

The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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UniProt Comments for IL28RA

IL28RA: The IL28RA/IL10RB dimer is a receptor for IL28A, IL28B and IL29. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Belongs to the type II cytokine receptor family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: integral to membrane; interleukin-28 receptor complex

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding

Biological Process: negative regulation of cell proliferation; mucosal immune response; cytokine and chemokine mediated signaling pathway; regulation of defense response to virus by host; defense response to virus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with IL28RA blocking peptide

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