CD10 (MME) ELISA Kit for Mouse

Name: Mouse MME ELISA Kit; CD10; MyBioSource
Brand: MyBioSource
SKU: MBS825073
Price: 640 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS825073

Sandwich ELISA for quantitative detection of Mouse CD10 concentrations. More details

$640 / 96 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

CD10 (MME), ELISA Kit

Full Product Name

Mouse CD10 ELISA Kit

Product Gene Name

MME elisa kit

Product Synonym Names

EPN; Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; CD10

Species Reactivity

Mouse

Assay Type

Sandwich

Samples

Cell Culture Supernatants, Serum, Plasma

Detection Range

93.7 pg/ml - 6000 pg/ml

Sensitivity

10 pg/ml

Preparation and Storage

Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.

Molecular Weight

85,702 Da

3D Structure

ModBase 3D Structure for Q61391

Detection Method

Colorimetric

Applications Tested/Suitable for MME elisa kit

Sandwich ELISA (SE)

Other Notes

Small volumes of MME elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MME purchase

MBS825073 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CD10 (MME) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MME. The ELISA analytical biochemical technique of the MBS825073 kit is based on MME antibody-MME antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MME antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MME. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for MME. It may not necessarily be applicable to this product.

NCBI GI #

575403040

NCBI GeneID

17380

NCBI Accession #

NP_001276391.1

UniProt Primary Accession #

Q61391

UniProt Secondary Accession #

Q6NXX5; Q8K251

UniProt Related Accession #

Q61391

GenBank Nucleotide #

NM_001289462.1

NCBI Official Full Name

neprilysin

NCBI Official Synonym Full Names

membrane metallo endopeptidase

NCBI Official Symbol

Mme

NCBI Official Synonym Symbols

NEP; SFE; CD10; CALLA; C85356; 6030454K05Rik

UniProt Protein Name

Neprilysin

UniProt Synonym Protein Names

Atriopeptidase; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; CD_antigen: CD10

Protein Family

Neprilysin

UniProt Gene Name

Mme

UniProt Synonym Gene Names

NEP; Neutral endopeptidase; SFE

UniProt Entry Name

NEP_MOUSE

NCBI Protein Information

neprilysin; enkephalinase; atriopeptidase; skin fibroblast elastase; neutral endopeptidase 24.11; common acute lymphoblastic leukemia antigen

UniProt Comments for MME

CD10: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV- inducible elastase activity toward skin preelastic and elastic fibers. Inhibited in a dose dependent manner by opiorphin. Belongs to the peptidase M13 family.

Protein type: Membrane protein, integral; Protease; EC 3.4.24.11

Cellular Component: synaptic vesicle; focal adhesion; membrane; axon; dendrite; cytoplasm; plasma membrane; integral to membrane; synapse; brush border

Molecular Function: peptidase activity; hydrolase activity; metallopeptidase activity; zinc ion binding; metalloendopeptidase activity; metal ion binding; endopeptidase activity; exopeptidase activity; peptide binding

Biological Process: peptide metabolic process; beta-amyloid metabolic process; creatinine metabolic process; sensory perception of pain; proteolysis

Research Articles on MME

1. Cell hypoxia in neuroblastoma cells results in up-regulation of neprilysin expression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with MME elisa kit

Products by Pathway	Pathway Diagram
Alzheimer's Disease Pathway antibodies	Alzheimer's Disease Pathway Diagram
Alzheimer's Disease Pathway antibodies	Alzheimer's Disease Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Metabolism Of Angiotensinogen To Angiotensins Pathway antibodies	Metabolism Of Angiotensinogen To Angiotensins Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Peptide Hormone Metabolism Pathway antibodies	Peptide Hormone Metabolism Pathway Diagram
Protein Digestion And Absorption Pathway antibodies	Protein Digestion And Absorption Pathway Diagram
Protein Digestion And Absorption Pathway antibodies	Protein Digestion And Absorption Pathway Diagram
Renin-angiotensin System Pathway antibodies	Renin-angiotensin System Pathway Diagram

Diseases associated with MME elisa kit

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>22 publications with MME and Nervous System Diseases
Carcinoma Antibodies	>17 publications with MME and Carcinoma
Heart Diseases Antibodies	>16 publications with MME and Heart Diseases
Kidney Diseases Antibodies	>14 publications with MME and Kidney Diseases
Necrosis Antibodies	>13 publications with MME and Necrosis
Inflammation Antibodies	>11 publications with MME and Inflammation
Neoplasms, Experimental Antibodies	>11 publications with MME and Neoplasms, Experimental
Lung Diseases Antibodies	>10 publications with MME and Lung Diseases
Disease Models, Animal Antibodies	>10 publications with MME and Disease Models, Animal
Edema Antibodies	>7 publications with MME and Edema

Organs/Tissues associated with MME elisa kit

Organ/Tissue Name	Pubmed Publications
Other Antibodies	>71 publications with MME and Other
Brain Antibodies	>23 publications with MME and Brain
Liver Antibodies	>21 publications with MME and Liver
Lung Antibodies	>18 publications with MME and Lung
Kidney Antibodies	>16 publications with MME and Kidney
Eye Antibodies	>9 publications with MME and Eye
Skin Antibodies	>9 publications with MME and Skin
Prostate Antibodies	>6 publications with MME and Prostate
Ovary Antibodies	>3 publications with MME and Ovary
Thyroid Antibodies	>3 publications with MME and Thyroid