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CDKL1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS829094

MBS829094 is an antibody targeting CDKL1. Reactive in Human, Mouse. Host: Rabbit. Rabbit polyclonal antibody to CDKL1 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CDKL1, Polyclonal Antibody
Full Product Name
Anti-CDKL1 Antibody
Product Gene Name
Product Synonym Names
Cyclin-dependent kinase-like 1; Protein kinase p42 KKIALRE; Serine/threonine-protein kinase KKIALRE
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of CDKL1 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
CDKL1 peptide (MBS829355) is used for blocking the activity of CDKL1 antibody (MBS829094)
Molecular Weight
108,931 Da
OMIM
603441
3D Structure
ModBase 3D Structure for Q00532
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CDKL1. The exact sequence is proprietary.
Applications Tested/Suitable for anti-CDKL1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CDKL1 antibody
WB (1/500 - 1/1000), IHC (1/100 - 1/200)

Western Blot (WB) of anti-CDKL1 antibody

Western blot analysis of CDKL1 expression in HEK293T (A), NIH3T3 (B) whole cell lysates.
Rabbit Anti-CDKL1 Polyclonal Antibody – Cat# MBS829094

Immunohistochemistry (IHC) of anti-CDKL1 antibody

Immunohistochemical analysis of CDKL1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-CDKL1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS829094

Other Notes

Small volumes of anti-CDKL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CDKL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cyclin-dependent kinase-like 1 isoform 1
NCBI Official Synonym Full Names
cyclin-dependent kinase-like 1 (CDC2-related kinase)
NCBI Official Symbol
CDKL1
NCBI Official Synonym Symbols
P42; KKIALRE
UniProt Protein Name
Cyclin-dependent kinase-like 1
UniProt Synonym Protein Names
Protein kinase p42 KKIALRE; Serine/threonine-protein kinase KKIALRE
UniProt Gene Name
CDKL1
UniProt Entry Name
CDKL1_HUMAN
NCBI Protein Information
cyclin-dependent kinase-like 1

NCBI Summary for CDKL1

This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

UniProt Comments for CDKL1

CDKL1: a protein kinase of the CDKL family. Accumulates primarily in the nucleus.

Protein type: Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor); Cell cycle regulation; EC 2.7.11.22; Kinase, protein; CMGC group; CDKL family

Chromosomal Location of Human Ortholog: 14q21.3

Cellular Component: cytoplasm; nucleus

Molecular Function: cyclin-dependent protein kinase activity; ATP binding

Biological Process: regulation of cell cycle; heart development; protein amino acid phosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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