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CRYAB Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS831956

MBS831956 is an antibody targeting CRYAB. Also known as CRYAB antibody. Host: Mouse. Mouse monoclonal CRYAB antibody More details

$1615 / 0.1 mL +2 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CRYAB, Monoclonal Antibody
Full Product Name
CRYAB antibody
Product Gene Name
anti-CRYAB antibody
Product Synonym Names
Monoclonal CRYAB; Anti-CRYAB; Crystallin Alpha B; CRYA2; CTPP2; HSPB5
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3 E3
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
CRYAB antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
20,129 Da
3D Structure
ModBase 3D Structure for Q7M2W6
Cross-Reactivity
Human
Immunogen
CRYAB antibody was raised in mouse using a protein expressed in 293T cell transfected with human CRYAB expression vector as the immunogen.

Product Categories/Family for anti-CRYAB antibody

Cell Biology
Applications Tested/Suitable for anti-CRYAB antibody
Western Blot (WB)
Application Notes for anti-CRYAB antibody
WB: 1:2000

Western Blot (WB) of anti-CRYAB antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant CRYAB protein (Right) or empty vector (Left) detected with CRYAB antibody
Mouse Anti-CRYAB Monoclonal Antibody – Cat# MBS831956

Other Notes

Small volumes of anti-CRYAB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CRYAB. It may not necessarily be applicable to this product.

NCBI GI #
169882027
NCBI GeneID
100519789
NCBI Accession #
ACA97071.1
UniProt Primary Accession #
Q7M2W6
UniProt Related Accession #
Q7M2W6
NCBI Official Full Name
CRYAB
NCBI Official Symbol
CRYAB
UniProt Protein Name
Alpha-crystallin B chain
UniProt Synonym Protein Names
Alpha(B)-crystallin
Protein Family
Alpha-crystallin
UniProt Gene Name
CRYAB
UniProt Entry Name
CRYAB_PIG
NCBI Protein Information
crystallin, alpha B; Alpha(B)-crystallin; Alpha-crystallin B chain

UniProt Comments for CRYAB

CRYAB: a major structural protein of the eye lens. A member of the small heat shock protein (sHSP also known as the HSP20) family. Alpha-B is expressed in the lens as well as other tissues. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy.

Protein type: Heat shock protein; Chaperone

Cellular Component: mitochondrion; cytoplasm; plasma membrane; Z disc; cytosol; nucleus

Molecular Function: protein homodimerization activity; metal ion binding; unfolded protein binding; structural constituent of eye lens

Biological Process: tubulin folding; lens development in camera-type eye; muscle development; negative regulation of intracellular transport; response to hydrogen peroxide; response to hypoxia; negative regulation of caspase activity; protein homooligomerization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CRYAB antibody

 Reference Product  PubMed Publications
 HSP27 antibody  >30 publications with CRYAB and HSP27
 CASP3 antibody  >9 publications with CRYAB and CASP3
 VEGFA antibody  >2 publications with CRYAB and VEGFA
 TP53 antibody  >2 publications with CRYAB and TP53
 DRD2 antibody  >1 publications with CRYAB and DRD2

Pathways associated with anti-CRYAB antibody

 Products by Pathway  Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram

Diseases associated with anti-CRYAB antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >64 publications with CRYAB and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >58 publications with CRYAB and Cardiovascular Diseases
 Heart Diseases Antibodies  >55 publications with CRYAB and Heart Diseases
 Cataract Antibodies  >41 publications with CRYAB and Cataract
 Disease Models, Animal Antibodies  >29 publications with CRYAB and Disease Models, Animal
 Brain Diseases Antibodies  >22 publications with CRYAB and Brain Diseases
 Neurodegenerative Diseases Antibodies  >18 publications with CRYAB and Neurodegenerative Diseases
 Breast Neoplasms Antibodies  >16 publications with CRYAB and Breast Neoplasms
 Inflammation Antibodies  >14 publications with CRYAB and Inflammation
 Necrosis Antibodies  >9 publications with CRYAB and Necrosis
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