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Keratin K75 (KRT75) Antibody – Guinea Pig Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS835656

MBS835656 is an antibody targeting KRT75. Also known as Keratin K75 antibody. Host: Guinea Pig. Guinea Pig polyclonal Keratin K75 antibody More details

$1340 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Keratin K75 (KRT75), Polyclonal Antibody
Full Product Name
Keratin K75 antibody
Product Gene Name
Product Synonym Names
Polyclonal Keratin K75; Anti Keratin K75; Keratin K-75; K6HF; CK-75; K75; Cytokeratin 75; KB18; PFB; Keratin K 75; Keratin K75
Clonality
Polyclonal
Host
Guinea Pig
Form/Format
Supplied in liquid form. Contains 0.09% sodium azide
Specificity
Human Keratin K75
Preparation and Storage
Store at 2-8 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
59,560 Da
OMIM
600628
3D Structure
ModBase 3D Structure for O95678
Cross-Reactivity
Mouse
Immunogen
Keratin K75 antibody was raised in Guinea Pig using synthetic peptide of human type II keratin K75 coupled to KLH as the immunogen.

Product Categories/Family for anti-KRT75 antibody

Applications Tested/Suitable for anti-KRT75 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-KRT75 antibody
IHC: 1:100-200
WB: 1:2000

Other Notes

Small volumes of anti-KRT75 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KRT75. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
keratin, type II cytoskeletal 75
NCBI Official Synonym Full Names
keratin 75, type II
NCBI Official Symbol
KRT75
NCBI Official Synonym Symbols
PFB; K6HF; KB18
UniProt Protein Name
Keratin, type II cytoskeletal 75
UniProt Synonym Protein Names
Cytokeratin-75; CK-75; Keratin-6 hair follicle; hK6hf; Keratin-75; K75; Type II keratin-K6hf; Type-II keratin Kb18
Protein Family
UniProt Gene Name
KRT75
UniProt Synonym Gene Names
K6HF; KB18; CK-75; hK6hf; K75
UniProt Entry Name
K2C75_HUMAN
NCBI Protein Information
keratin, type II cytoskeletal 75

NCBI Summary for KRT75

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS). [provided by RefSeq, Oct 2008]
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UniProt Comments for KRT75

KRT75: Plays a central role in hair and nail formation. Essential component of keratin intermediate filaments in the companion layer of the hair follicle. Defects in KRT75 may be a cause of loose anagen hair syndrome (LAHS). In LAHS, anagen hairs are easily pulled from the scalp. The hair is relatively sparse and does not grow long. Hair of fair color and hair shafts of reduced caliber, and an early age of onset are features. Usually the hairs are not fragile and there are no areas of breakage. Belongs to the intermediate filament family.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: keratin filament

Molecular Function: structural molecule activity

Biological Process: hemopoietic progenitor cell differentiation

Disease: Pseudofolliculitis Barbae
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-KRT75 antibody

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