snRNP Recombinant Protein

Name: snRNP Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS835881
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS835881

MBS835881 is a recombinant protein targeting snRNP. Also known as snRNP protein. Purified recombinant snRNP protein More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

snRNP, Recombinant Protein

Full Product Name

snRNP protein

Product Gene Name

snRNP recombinant protein

Product Synonym Names

Small Ribonucleoprotein; snRNP

Form/Format

Supplied in lyophilized form with 25 mM Tris, 190 mM glycine, 0.025% (w/v) SDS, pH 8.3

Concentration

1 mg/ml (lot specific)

Preparation and Storage

Store at 2-8 degree C in lyophilized form. Following reconstitution aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Molecular Weight

70 kDa

OMIM

607282

3D Structure

ModBase 3D Structure for Q6FGG1

Protein Type

Recombinant

Expression System

HeLa cells

Product Categories/Family for snRNP recombinant protein

DNA & RNA

Applications Tested/Suitable for snRNP recombinant protein

User optimized

Other Notes

Small volumes of snRNP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for snRNP. It may not necessarily be applicable to this product.

NCBI GI #

4529895

NCBI GeneID

57819

NCBI Accession #

AAD21818.1

UniProt Primary Accession #

Q6FGG1

UniProt Secondary Accession #

Q6FGG1

UniProt Related Accession #

Q9Y333

NCBI Official Full Name

snRNP

NCBI Official Synonym Full Names

LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated

NCBI Official Symbol

LSM2

NCBI Official Synonym Symbols

G7B; snRNP; C6orf28; YBL026W

UniProt Protein Name

U6 snRNA-associated Sm-like protein LSm2

UniProt Synonym Protein Names

Protein G7b; Small nuclear ribonuclear protein D homolog; snRNP core Sm-like protein Sm-x5

Protein Family

Splicing factor

UniProt Gene Name

LSM2

UniProt Synonym Gene Names

C6orf28; G7B

UniProt Entry Name

LSM2_HUMAN

NCBI Protein Information

U6 snRNA-associated Sm-like protein LSm2

NCBI Summary for snRNP

This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19. [provided by RefSeq, Nov 2011]

UniProt Comments for snRNP

LSM2: Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing. Identified in the spliceosome C complex. LSm subunits form a heteromer with a doughnut shape. Belongs to the snRNP Sm proteins family.

Protein type: RNA splicing; Spliceosome; RNA-binding

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: nucleoplasm; cytosol

Molecular Function: protein binding; Ral GTPase binding; protein kinase binding; U6 snRNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; mRNA catabolic process, deadenylation-dependent decay

Research Articles on snRNP

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with snRNP recombinant protein

Products by Pathway	Pathway Diagram
Deadenylation-dependent MRNA Decay Pathway antibodies	Deadenylation-dependent MRNA Decay Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Lsm 1-7 Complex Pathway antibodies	Lsm 1-7 Complex Pathway Diagram
Lsm 1-7 Complex Pathway antibodies	Lsm 1-7 Complex Pathway Diagram
Lsm 2-8 Complex Pathway antibodies	Lsm 2-8 Complex Pathway Diagram
Lsm 2-8 Complex Pathway antibodies	Lsm 2-8 Complex Pathway Diagram
Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies	Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
RNA Degradation Pathway antibodies	RNA Degradation Pathway Diagram
RNA Degradation Pathway antibodies	RNA Degradation Pathway Diagram
Spliceosome Pathway antibodies	Spliceosome Pathway Diagram

Diseases associated with snRNP recombinant protein

Disease Name	Pubmed Publications
Fibrosis Antibodies	>3 publications with snRNP and Fibrosis
Liver Diseases Antibodies	>2 publications with snRNP and Liver Diseases
Ovarian Diseases Antibodies	>1 publications with snRNP and Ovarian Diseases
Kidney Diseases Antibodies	>1 publications with snRNP and Kidney Diseases

Organs/Tissues associated with snRNP recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>4 publications with snRNP and Liver
Blood Antibodies	>3 publications with snRNP and Blood
Kidney Antibodies	>2 publications with snRNP and Kidney
Thymus Antibodies	>1 publications with snRNP and Thymus
Skin Antibodies	>1 publications with snRNP and Skin
Testis Antibodies	>1 publications with snRNP and Testis
Heart Antibodies	>1 publications with snRNP and Heart
Brain Antibodies	>1 publications with snRNP and Brain