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LY-3381916

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400369

LY-3381916 is a potent, selective and brain permeant IDO1 (Indoleamine 2, 3-Dioxygenase1) inhibitor. LY-3381916 specifically targets and binds to IDO1, a cytosolic enzyme responsible for the oxidation of the amino acid tryptophan into the immunosuppressive… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
LY-3381916, Biochemical
Full Product Name
LY-3381916
Product Gene Name
LY-3381916 biochemical
Product Synonym Names
(R)-4-fluoro-N-(1-(1-(tetrahydro-2H-pyran-4-carbonyl)indolin-5-yl)ethyl)benzamide, IDO1IN5, LY 3381916, IDO1-IN-5
Form/Format
Crystalline solid
Purity/Purification
>=98%
Specificity
A potent; brain-permeant IDO1 inhibitor
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
396.46
Solubilities
>100mg/ml DMSO
Molecular Formula
C??H??FN?O?
InChi
InChI=1S/C23H25FN2O3/c1-15(25-22(27)16-2-5-20(24)6-3-16)18-4-7-21-19(14-18)8-11-26(21)23(28)17-9-12-29-13-10-17/h2-7; 14-15; 17H; 8-13H2; 1H3; (H; 25; 27)/t15-/m1/s1
InChi Key
NUBWFWVVKLRSHS-OAHLLOKOSA-N
SMILES
FC1=CC=C(C(N[C@H](C)C2=CC=C(N(C(C3CCOCC3)=O)CC4)C4=C2)=O)C=C1
CAS Number
2166616-75-5

Product Categories/Family for LY-3381916 biochemical

Web Categories; Enzyme Inhibitors; Indoleamine 2; 3-dioxygenase (IDO) Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z)

Structure of LY-3381916 biochemical

LY-3381916 Biochemical – Cat# MBS8400369

Other Notes

Small volumes of LY-3381916 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LY-3381916 purchase

MBS8400369 is a biochemical targeting LY-3381916.
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