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OSS-128167

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400400

OSS-128167 is a potent and selective inhibitor of sirtuin 6 (SIRT6; IC50 = 89uM). It displays selectivity for SIRT6 over SIRT1 and SIRT2 (IC50s = 1, 578 and 751uM, respectively). OSS-128167 increases acetylation of histone H3 lysine 9 (H3K9) and glucose… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
OSS-128167, Biochemical
Full Product Name
OSS-128167
Product Gene Name
OSS-128167 biochemical
Product Synonym Names
5-[[3-[(2-furanylcarbonyl)amino]benzoyl]amino]-2-hydroxy-benzoic acid, OSS128167
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Specificity
A potent and selective SIRT6 (Sirtuin-6) inhibitor
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
366.3
Solubilities
~30mg/ml DMSO
Molecular Formula
C??H??N?O?
InChi
InChI=1S/C19H14N2O6/c22-15-7-6-13(10-14(15)19(25)26)20-17(23)11-3-1-4-12(9-11)21-18(24)16-5-2-8-27-16/h1-10; 22H; (H; 20; 23)(H; 21; 24)(H; 25; 26)
InChi Key
HTJWLEGCECXGSQ-UHFFFAOYSA-N
SMILES
C1=CC(=CC(=C1)NC(=O)C2=CC=CO2)C(=O)NC3=CC(=C(C=C3)O)C(=O)O
CAS Number
887686-02-4
PubChem CID
6496840

Product Categories/Family for OSS-128167 biochemical

Web Categories; Enzyme Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals; Biochemicals (A-Z); Cancer Research; Epigenetic Regulation; Eraser Enzymes; Sirtuins (SIRTs); SIRT Inhibitors

Structure of OSS-128167 biochemical

OSS-128167 Biochemical – Cat# MBS8400400

Product References and Citations for OSS-128167 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/6496840

Other Notes

Small volumes of OSS-128167 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OSS-128167 purchase

MBS8400400 is a biochemical targeting OSS-128167.
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