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C87

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400502

C87 is an inhibitor of Tumor Necrosis Factor alpha (TNFalpha). It binds to human TNFalpha with a KD of 110nM and potently inhibits TNFalpha-induced cytotoxicity in L929 cells with an IC50 of 8.73uM. It effectively blocks TNFalpha-triggered signaling pathways… More details

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Product Documentation
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Testing Data View PDF
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Product Overview

Product Name
C87, Biochemical
Full Product Name
C87
Product Gene Name
C87 biochemical
Product Synonym Names
4-[(4-chloro-3-nitrophenyl)diazenyl]-5-phenyl-2-(4-phenyl-1, 3-thiazol-2-yl)-1H-pyrazol-3-one; 3-phenyl-1-(4-phenyl-1, 3-thiazol-2-yl)-1H-pyrazole-4, 5-dione 4-({4-chloro-3-nitrophenyl}hydrazone); 4-[(E)-2-(4-chloro-3-nitrophenyl)hydrazono]-5-phenyl-2-(4-phenyl-1, 3-thiazol-2-yl)-2, 4-dihydro-3H-pyrazol-3-one; TNF-TNFR Signaling Inhibitor IV
Form/Format
Orange Red Solid
Purity/Purification
>=98%
Specificity
An inhibitor of Tumor Necrosis Factor alpha
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
502.93
Solubilities
5mg/ml in DMSO
Molecular Formula
C??H??ClN?O?S
InChi
InChI=1S/C24H15ClN6O3S/c25-18-12-11-17(13-20(18)31(33)34)27-28-22-21(16-9-5-2-6-10-16)29-30(23(22)32)24-26-19(14-35-24)15-7-3-1-4-8-15/h1-14; 29H
InChi Key
HTEQQWJUYYUNQG-UHFFFAOYSA-N
SMILES
C1=CC=C(C=C1)C2=CSC(=N2)N3C(=O)C(=C(N3)C4=CC=CC=C4)N=NC5=CC(=C(C=C5)Cl)[N+](=O)[O-]
CAS Number
332420-90-3
MDL Number
MFCD00810005
PubChem CID
4016403

Product Categories/Family for C87 biochemical

Web Categories; Biochemicals; Biochemicals(A-Z); Immunology; Inflammation; Enzyme Inhibitors; Enzyme Inhibitors (A-Z)

Structure of C87 biochemical

C87 Biochemical – Cat# MBS8400502

Product References and Citations for C87 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/4016403

Other Notes

Small volumes of C87 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for C87 purchase

MBS8400502 is a biochemical targeting C87.
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