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ONC-201

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400515

ONC-201 is an orally active transcriptional inducer of Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). It induces TRAIL in a p53-independent manner at concentrations of 1.25uM-5uM and crosses the blood-brain barrier. It inactivates kinases… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
ONC-201, Biochemical
Full Product Name
ONC-201
Product Gene Name
ONC-201 biochemical
Product Synonym Names
11-benzyl-7-[(2-methylphenyl)methyl]-2, 5, 7, 11-tetrazatricyclo[7.4.0.02, 6]trideca-1(9), 5-dien-8-one; 7-Benzyl-4-(2-methylbenzyl)-1, 2, 6, 7, 8, 9-hexahydroimidazo[1, 2-A]pyrido[3, 4-E]pyrimidin-5(4H)-one; 2, 4, 6, 7, 8, 9-hexahydro-4-[(2-methylphenyl)methyl]-7-(phenylmethyl)-imidazo[1, 2-a]pyrido[3, 4-e]pyrimidin-5(1H)-one; TIC10; TRAIL-inducing compound 10
Form/Format
White to off-white powder
Purity/Purification
>=98%
Specificity
A transcriptional inducer of TRAIL
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
386.49
Solubilities
~20mg/ml in DMF; ~10mg/ml in ethanol; ~1mg/ml in DMSO
Molecular Formula
C??H??N?O
InChi
InChI=1S/C24H26N4O/c1-18-7-5-6-10-20(18)16-28-23(29)21-17-26(15-19-8-3-2-4-9-19)13-11-22(21)27-14-12-25-24(27)28/h2-10H; 11-17H2; 1H3
InChi Key
VLULRUCCHYVXOH-UHFFFAOYSA-N
SMILES
CC1=CC=CC=C1CN2C(=O)C3=C(CCN(C3)CC4=CC=CC=C4)N5C2=NCC5CC1=CC=CC=C1CN2C(=O)C3=C(CCN(C3)CC4=CC=CC=C4)N5C2=NCC5
CAS Number
1616632-77-9
MDL Number
MFCD28118993
PubChem CID
73777259

Product Categories/Family for ONC-201 biochemical

Web Categories; Biochemicals; Biochemicals (A-Z); Apoptosis & Related Products; Apoptosis Inducers; Cancer Research; Anticancer Agents

Structure of ONC-201 biochemical

ONC-201 Biochemical – Cat# MBS8400515

Product References and Citations for ONC-201 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/73777259

Other Notes

Small volumes of ONC-201 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ONC-201 purchase

MBS8400515 is a biochemical targeting ONC-201.
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