Rabbit Anti-NAMPT Polyclonal Antibody – Cat# MBS840607

Visfatin (NAMPT) Antibody – Rabbit Polyclonal

Name: NAMPT Antibody; Polyclonal; Rabbit; Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS840607
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840607

Background: Visfatin is a cytokine highly expressed in visceral fat and blood. This protein has also been reported to be a cytokine (PBEF) that promotes B cell maturation and inhibits neutrophil apoptosis. Visfatin is thomught to have insulin-like activities… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Visfatin (Nampt), Polyclonal Antibody

Full Product Name

Visfatin Antibody

Product Gene Name

anti-Nampt antibody

Product Synonym Names

Nampt; Nicotinamide phosphoribosyltransferase; Pre-B-cell colony-enhancing factor 1 homolog; PBEF; visceral fat-derived hormone

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Rat

Form/Format

100 ug (0.5 mg/ml) affinity purified rabbit anti-rat Visfatin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA and 0.01% thimerosal
Appearance: Colorless liquid

Purity/Purification

Affinity purified

Concentration

0.5 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

55,438 Da

3D Structure

ModBase 3D Structure for Q80Z29

Immunogen

E. coli expressed recombinant rat Visfatin

Handling

The antibody solution should be gently mixed before use.

Applications Tested/Suitable for anti-Nampt antibody

Western Blot (WB)

Application Notes for anti-Nampt antibody

Western blot (0.5-4 ug/ml). Recombinant rat Visfatin can be used as a positive control. However, the optimal conditions should be determined individually. Other applications have not been tested.

Other Notes

Small volumes of anti-Nampt antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Nampt purchase

MBS840607 is an antibody targeting Nampt. Also known as Visfatin Antibody. Reactive in Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Nampt. It may not necessarily be applicable to this product.

NCBI GI #

29293813

NCBI GeneID

297508

NCBI Accession #

NP_808789.1

UniProt Primary Accession #

Q80Z29

UniProt Secondary Accession #

Q2VT47

GenBank Nucleotide #

NM_177928.3

NCBI Official Full Name

nicotinamide phosphoribosyltransferase

UniProt Protein Name

Nicotinamide phosphoribosyltransferase

UniProt Synonym Protein Names

Pre-B-cell colony-enhancing factor 1 homolog; PBEF; Visfatin

Protein Family

Nicotinamide phosphoribosyltransferase

UniProt Gene Name

Nampt

UniProt Synonym Gene Names

Pbef1; NAmPRTase; Nampt; PBEF

UniProt Entry Name

NAMPT_RAT

NCBI Summary for Nampt

has similarity to cytokines but is not secreted; localized to the nucleus and cytoplasm, changes in subcellular localization may be associated with the cell cycle [RGD, Feb 2006]

UniProt Comments for Nampt

PBEF: an ubiquitous protein originally described as a cytokine which acts on early B-lineage precursor cells. Other reports indicate that PBEF is not a cytokine-like secreted protein but an intracellular protein associated with the cell cycle. Contains a catalytically active nicotinate phosphoribosyltransferase domain, an enzyme involved in nicotinamide adenine dinucleotide (NAD) biosynthesis.

Protein type: EC 2.4.2.12; Cytokine; Cell cycle regulation; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Transferase

Cellular Component: extracellular space; cytoplasm; nucleus

Molecular Function: protein homodimerization activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; cytokine activity; drug binding; nicotinamide phosphoribosyltransferase activity

Biological Process: NAD biosynthetic process; positive regulation of smooth muscle cell proliferation; insulin receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; female pregnancy; circadian regulation of gene expression; response to organic cyclic substance; positive regulation of nitric-oxide synthase biosynthetic process

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Nampt antibody

Reference Product	PubMed Publications
Sirt1 antibody	>95 publications with Nampt and Sirt1
Clock antibody	>21 publications with Nampt and Clock
Arntl antibody	>7 publications with Nampt and Arntl
Nt5e antibody	>2 publications with Nampt and Nt5e
Nmnat1 antibody	>2 publications with Nampt and Nmnat1
Nmnat2 antibody	>2 publications with Nampt and Nmnat2

Pathways associated with anti-Nampt antibody

Products by Pathway	Pathway Diagram
Adipogenesis Pathway antibodies	Adipogenesis Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Vitamins And Cofactors Pathway antibodies	Metabolism Of Vitamins And Cofactors Pathway Diagram
Metabolism Of Water-soluble Vitamins And Cofactors Pathway antibodies	Metabolism Of Water-soluble Vitamins And Cofactors Pathway Diagram
Nicotinamide Salvaging Pathway antibodies	Nicotinamide Salvaging Pathway Diagram
Nicotinate And Nicotinamide Metabolism Pathway antibodies	Nicotinate And Nicotinamide Metabolism Pathway Diagram
Nicotinate And Nicotinamide Metabolism Pathway antibodies	Nicotinate And Nicotinamide Metabolism Pathway Diagram
Nicotinate Metabolism Pathway antibodies	Nicotinate Metabolism Pathway Diagram

Diseases associated with anti-Nampt antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>83 publications with Nampt and Inflammation
Obesity Antibodies	>72 publications with Nampt and Obesity
Insulin Resistance Antibodies	>52 publications with Nampt and Insulin Resistance
Disease Models, Animal Antibodies	>25 publications with Nampt and Disease Models, Animal
Necrosis Antibodies	>23 publications with Nampt and Necrosis
Liver Diseases Antibodies	>21 publications with Nampt and Liver Diseases
Atherosclerosis Antibodies	>20 publications with Nampt and Atherosclerosis
Nervous System Diseases Antibodies	>18 publications with Nampt and Nervous System Diseases
Fatty Liver Antibodies	>15 publications with Nampt and Fatty Liver
Heart Diseases Antibodies	>14 publications with Nampt and Heart Diseases

Organs/Tissues associated with anti-Nampt antibody

Organ/Tissue Name	Pubmed Publications
Adipose Tissue Antibodies	>46 publications with Nampt and Adipose Tissue
Liver Antibodies	>43 publications with Nampt and Liver
Muscle Antibodies	>42 publications with Nampt and Muscle
Brain Antibodies	>26 publications with Nampt and Brain
Heart Antibodies	>24 publications with Nampt and Heart
Connective Tissue Antibodies	>24 publications with Nampt and Connective Tissue
Lung Antibodies	>16 publications with Nampt and Lung
Nerve Antibodies	>12 publications with Nampt and Nerve
Pancreas Antibodies	>11 publications with Nampt and Pancreas
Ovary Antibodies	>6 publications with Nampt and Ovary