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TLR11 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840654

Background: The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLRs require adapter molecule such as MyD88 and TIRAP to activate various… More details

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Testing Data View PDF
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Product Overview

Product Name
TLR11, Polyclonal Antibody
Full Product Name
TLR11 Antibody
Product Gene Name
Product Synonym Names
Toll-like receptor 11
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
100 ug (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Appearance: Colorless liquid
Purity/Purification
Affinity purified
Concentration
0.5 mg/ml (lot specific)
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
105,873 Da
3D Structure
ModBase 3D Structure for Q6R5P0
Immunogen
Synthetic peptide surrounding amino acid 793 of mouse TLR11
Handling
The antibody solution should be gently mixed before use.
Applications Tested/Suitable for anti-TLR11 antibody
Western Blot (WB)
Application Notes for anti-TLR11 antibody
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~70-90 kDa of TLR11 in Jurkat cell lysate. Reactivity to other species has not been tested.

Testing Data of anti-TLR11 antibody

Rabbit Anti-TLR11 Polyclonal Antibody – Cat# MBS840654

Other Notes

Small volumes of anti-TLR11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TLR11 purchase

MBS840654 is an antibody targeting TLR11. Also known as TLR11 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TLR11. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
toll-like receptor 11
NCBI Official Synonym Full Names
toll-like receptor 11
NCBI Official Symbol
Tlr11
NCBI Official Synonym Symbols
Gm287
UniProt Protein Name
Toll-like receptor 11
Protein Family
UniProt Gene Name
Tlr11
UniProt Synonym Gene Names
Gm287
UniProt Entry Name
TLR11_MOUSE
NCBI Protein Information
toll-like receptor 11

UniProt Comments for TLR11

Tlr11: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Belongs to the Toll-like receptor family.

Cellular Component: membrane; integral to membrane

Molecular Function: protein binding; transmembrane receptor activity

Biological Process: MyD88-dependent toll-like receptor signaling pathway; regulation of cytokine secretion; response to bacterium; immune system process; innate immune response; signal transduction; inflammatory response; toll-like receptor 11 signaling pathway; positive regulation of inflammatory response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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