Rabbit Anti-EHMT2 Polyclonal Antibody – Cat# MBS840680

EHMT2 Antibody – Rabbit Polyclonal

Name: EHMT2 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS840680
Price: 475 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840680

Polyclonal antibody to detect EHMT2 in human, mouse and rat samples.Background: G9a, also known as Euchromatic histone-lysine N-methyltransferase 2 (EHMT2), is a member of a family of histone lysine methyltransferases. Recombinant G9a can mono-, di- and… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

EHMT2, Polyclonal Antibody

Full Product Name

EHMT2 Antibody

Product Gene Name

anti-EHMT2 antibody

Product Synonym Names

BAT8; C6orf30; DKFZp686H08213; FLJ35547; G9A; KMT1C; NG36; NG3

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

100 ug of antibody in 100 ul PBS containing 0.02% sodium azide, 50% glycerol, pH 7.3
Appearance: Colorless liquid

Purity/Purification

Affinity purified

Concentration

1 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

19,864 Da

OMIM

604599

3D Structure

ModBase 3D Structure for Q96KQ7

Immunogen

Recombinant protein of human EHMT2

Positive Control

Western Blot: Various cell lysates

Handling

The antibody solution should be gently mixed before use.

Product Categories/Family for anti-EHMT2 antibody

Epigenetics; Writer Enzymes; Protein Lysine Methyltransferases (PKMTs); AntibodiesAntibodies & Supporting Tools; Primary Antibodies (A-Z)

Applications Tested/Suitable for anti-EHMT2 antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-EHMT2 antibody

Western blot: 1:500 - 1:2000, IHC: 1:50 - 1:200.

Other Notes

Small volumes of anti-EHMT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EHMT2 purchase

MBS840680 is an antibody targeting EHMT2. Also known as EHMT2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EHMT2. It may not necessarily be applicable to this product.

NCBI GI #

574957264

NCBI GeneID

10919

NCBI Accession #

NP_001276342.1

UniProt Primary Accession #

Q96KQ7

UniProt Secondary Accession #

Q14349; Q5JP83; Q5JQ92; Q5JQA1; Q5JQG3; Q6PK06; Q96MH5; Q96QD0; Q9UQL8; Q9Y331; B0UZY2

UniProt Related Accession #

Q96KQ7

GenBank Nucleotide #

NM_001289413.1

NCBI Official Full Name

histone-lysine N-methyltransferase EHMT2 isoform c

NCBI Official Synonym Full Names

euchromatic histone-lysine N-methyltransferase 2

NCBI Official Symbol

EHMT2

NCBI Official Synonym Symbols

G9A; BAT8; GAT8; NG36; KMT1C; C6orf30

UniProt Protein Name

Histone-lysine N-methyltransferase EHMT2

UniProt Synonym Protein Names

Euchromatic histone-lysine N-methyltransferase 2; HLA-B-associated transcript 8; Histone H3-K9 methyltransferase 3; H3-K9-HMTase 3; Lysine N-methyltransferase 1C; Protein G9a

Protein Family

Histone-lysine N-methyltransferase

UniProt Gene Name

EHMT2

UniProt Synonym Gene Names

BAT8; C6orf30; G9A; KMT1C; NG36; H3-K9-HMTase 3

UniProt Entry Name

EHMT2_HUMAN

NCBI Protein Information

histone-lysine N-methyltransferase EHMT2

NCBI Summary for EHMT2

This gene is located in a gene cluster within the human major histocompatibility complex class III region on chromosome 6. This gene was thought to be two different genes, NG36 and G9a, adjacent to each other but recent publications show that there is only a single gene at this locus. The encoded protein is a histone methyltransferase, which may be involved in repression of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

UniProt Comments for EHMT2

EHMT2 iso4: Histone methyltransferase. Preferentially methylates 'Lys-9' of histone H3 and 'Lys-27' of histone H3 (in vitro). H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. Also methylates histone H1. Belongs to the histone-lysine methyltransferase family. Suvar3-9 subfamily. Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2. Interacts with GFI1B, WIZ and EHMT1. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Methyltransferase; Methyltransferase, protein lysine; EC 2.1.1.43; Amino Acid Metabolism - lysine degradation

Chromosomal Location of Human Ortholog: 6p21.31

Cellular Component: nucleoplasm; intermediate filament cytoskeleton; intracellular membrane-bound organelle; nuclear chromatin; nucleus

Molecular Function: protein binding; zinc ion binding; p53 binding; histone lysine N-methyltransferase activity (H3-K9 specific); protein-lysine N-methyltransferase activity; histone-lysine N-methyltransferase activity; histone lysine N-methyltransferase activity (H3-K27 specific)

Biological Process: histone methylation; establishment and/or maintenance of chromatin architecture; peptidyl-lysine di-methylation; DNA methylation; negative regulation of transcription from RNA polymerase II promoter; histone H3-K9 methylation; regulation of DNA replication

Research Articles on EHMT2

1. G9a contributes to multiple steps of ovarian cancer metastasis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EHMT2 antibody

Reference Product	PubMed Publications
DNMT1 antibody	>10 publications with EHMT2 and DNMT1
DNMT3A antibody	>5 publications with EHMT2 and DNMT3A
CBX3 antibody	>2 publications with EHMT2 and CBX3
CDYL antibody	>2 publications with EHMT2 and CDYL
WIZ antibody	>1 publications with EHMT2 and WIZ
KDM5A antibody	>1 publications with EHMT2 and KDM5A
PRDM1 antibody	>1 publications with EHMT2 and PRDM1

Diseases associated with anti-EHMT2 antibody

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>9 publications with EHMT2 and Breast Neoplasms
Adenocarcinoma Antibodies	>7 publications with EHMT2 and Adenocarcinoma
Inflammation Antibodies	>5 publications with EHMT2 and Inflammation
Nervous System Diseases Antibodies	>5 publications with EHMT2 and Nervous System Diseases
Necrosis Antibodies	>4 publications with EHMT2 and Necrosis
Neoplasm Metastasis Antibodies	>4 publications with EHMT2 and Neoplasm Metastasis
Lung Diseases Antibodies	>3 publications with EHMT2 and Lung Diseases
Carcinoma, Hepatocellular Antibodies	>3 publications with EHMT2 and Carcinoma, Hepatocellular
Neurobehavioral Manifestations Antibodies	>3 publications with EHMT2 and Neurobehavioral Manifestations
Lung Neoplasms Antibodies	>3 publications with EHMT2 and Lung Neoplasms

Organs/Tissues associated with anti-EHMT2 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>16 publications with EHMT2 and Blood
Liver Antibodies	>8 publications with EHMT2 and Liver
Lung Antibodies	>5 publications with EHMT2 and Lung
Brain Antibodies	>5 publications with EHMT2 and Brain
Thyroid Antibodies	>3 publications with EHMT2 and Thyroid
Bone Antibodies	>3 publications with EHMT2 and Bone
Testis Antibodies	>2 publications with EHMT2 and Testis
Lymph Antibodies	>2 publications with EHMT2 and Lymph
Placenta Antibodies	>2 publications with EHMT2 and Placenta
Lymph Node Antibodies	>2 publications with EHMT2 and Lymph Node