• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

RNASE3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2400290

RNASE3 Antibody, ECP Antibody, Ribonuclease 3 Antibody, RNase 3 Antibody, Cytotoxic ribonuclease Antibody, Eosinophil cationic protein Antibody, RNS3 Antibody Description: Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a… More details

$650 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RNASE3, Polyclonal Antibody
Full Product Name
Anti-RNASE3 Antibody (aa123-151) IHC-plus
Product Gene Name
anti-RNASE3 antibody
Product Synonym Names
Rabbit Polyclonal to Human RNASE3; Human RNASE3; ECP; Ribonuclease 3; RNase 3; Cytotoxic ribonuclease; Eosinophil cationic protein; RNS3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.09% sodium azide
Purity/Purification
Immunoaffinity purified
Specificity
Human RNASE3
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months.
For long term storage store at -20 degree C.
Molecular Weight
18,385 Da
OMIM
131398
3D Structure
ModBase 3D Structure for P12724
Immunogen
RNASE3 antibody was raised against kLH-conjugated synthetic peptide from C-terminal region of human RNASE3.
Immunogen Description
KLH-conjugated synthetic peptide from C-terminal region of human RNASE3.
Immunogen Type
Synthetic peptide
Antigen Modification
aa123-151
Target Species
Human
Applications Tested/Suitable for anti-RNASE3 antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-RNASE3 antibody
IF (1:10 - 1:50)
IHC-P (1:100)
WB (1:1000)

Immunohistochemistry - Paraffin (IHC) of anti-RNASE3 antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-RNASE3 Polyclonal Antibody – Cat# MBS2400290

Immunofluorescence (IF) of anti-RNASE3 antibody

Confocal immunofluorescence of RNASE3 Antibody with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Rabbit Anti-RNASE3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS2400290

Western Blot (WB) of anti-RNASE3 antibody

Western blot of lysate from human spleen tissue lysate, using RNASE3 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 35ug.
Rabbit Anti-RNASE3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS2400290

Western Blot (WB) of anti-RNASE3 antibody

RNASE3 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The RNASE3 antibody detected the RNASE3 protein (arrow).
Rabbit Anti-RNASE3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS2400290

Other Notes

Small volumes of anti-RNASE3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RNASE3 purchase

MBS2400290 is an antibody targeting RNASE3. Also known as Anti-RNASE3 Antibody (aa123-151) IHC-plus. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RNASE3. It may not necessarily be applicable to this product.

NCBI GI #
45243507
NCBI GeneID
6037
NCBI Accession #
NP_002926.2
UniProt Primary Accession #
P12724
UniProt Secondary Accession #
Q4VBC1; Q8WTP7; Q8WZ62; Q9GZN9
UniProt Related Accession #
P12724
GenBank Nucleotide #
NM_002935.2
NCBI Official Full Name
eosinophil cationic protein
NCBI Official Synonym Full Names
ribonuclease A family member 3
NCBI Official Symbol
RNASE3
NCBI Official Synonym Symbols
ECP; RNS3
UniProt Protein Name
Eosinophil cationic protein
UniProt Synonym Protein Names
Ribonuclease 3; RNase 3
Protein Family
Eosinophil cationic protein
UniProt Gene Name
RNASE3
UniProt Synonym Gene Names
ECP; RNS3; ECP; RNase 3
UniProt Entry Name
ECP_HUMAN
NCBI Protein Information
eosinophil cationic protein

NCBI Summary for RNASE3

The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014]

UniProt Comments for RNASE3

RNASE3: Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. Belongs to the pancreatic ribonuclease family.

Protein type: EC 3.1.27.-; Secreted, signal peptide; Ribonuclease; Secreted

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: extracellular region; extracellular space

Molecular Function: endonuclease activity; nucleic acid binding; ribonuclease activity

Biological Process: antibacterial humoral response; defense response to Gram-positive bacterium; innate immune response in mucosa; RNA catabolic process
Show more

Research Articles on RNASE3

1. drug eluting stent polymers increase eosinophil cationic protein levels following percutaneous coronary intervention independently of C-reactive protein

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RNASE3 antibody

 Reference Product  PubMed Publications
 CCL11 antibody  >4 publications with RNASE3 and CCL11
 EPX antibody  >4 publications with RNASE3 and EPX
 IL5 antibody  >1 publications with RNASE3 and IL5

Pathways associated with anti-RNASE3 antibody

 Products by Pathway  Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram

Diseases associated with anti-RNASE3 antibody

 Disease Name  Pubmed Publications
 Hypersensitivity Antibodies  >76 publications with RNASE3 and Hypersensitivity
 Respiratory Tract Diseases Antibodies  >69 publications with RNASE3 and Respiratory Tract Diseases
 Respiratory Hypersensitivity Antibodies  >59 publications with RNASE3 and Respiratory Hypersensitivity
 Asthma Antibodies  >59 publications with RNASE3 and Asthma
 Lung Diseases Antibodies  >52 publications with RNASE3 and Lung Diseases
 Lung Diseases, Obstructive Antibodies  >49 publications with RNASE3 and Lung Diseases, Obstructive
 Inflammation Antibodies  >47 publications with RNASE3 and Inflammation
 Rhinitis Antibodies  >23 publications with RNASE3 and Rhinitis
 Eosinophilia Antibodies  >20 publications with RNASE3 and Eosinophilia
 Rhinitis, Allergic, Seasonal Antibodies  >13 publications with RNASE3 and Rhinitis, Allergic, Seasonal

Organs/Tissues associated with anti-RNASE3 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >93 publications with RNASE3 and Blood
 Eye Antibodies  >2 publications with RNASE3 and Eye
 Brain Antibodies  >1 publications with RNASE3 and Brain
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000