Rabbit Anti-BRDT Polyclonal Antibody – Cat# MBS840743

BRDT Antibody – Rabbit Polyclonal

Name: BRDT Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS840743
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840743

Polyclonal Antibody to detect BRDT in human samplesBackground: BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

BRDT, Polyclonal Antibody

Full Product Name

BRDT Antibody

Product Gene Name

anti-BRDT antibody

Product Synonym Names

BrdT; Cancer/testis antigen 9; CT9; RING3-like protein

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

100 ug (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Appearance: Colorless liquid

Purity/Purification

Affinity Purified Antibody

Concentration

0.5 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

99,394 Da

OMIM

602144

3D Structure

ModBase 3D Structure for Q58F21

Immunogen

Recombinant protein BRDT (257-382 aa) (BV-M72)

Positive Control

Western blot: Recombinant protein

Handling

The antibody solution should be gently mixed before use.

Product Categories/Family for anti-BRDT antibody

Antibodies & Supporting Tools; Primary Antibodies (A-Z) Epigenetics; Reader Domains; Bromodomains; Antibodies and Blocking Peptides

Applications Tested/Suitable for anti-BRDT antibody

Western Blot (WB)

Application Notes for anti-BRDT antibody

Western blot: ~1:200

Other Notes

Small volumes of anti-BRDT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BRDT purchase

MBS840743 is an antibody targeting BRDT. Also known as BRDT Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BRDT. It may not necessarily be applicable to this product.

NCBI GI #

729042272

NCBI GeneID

676

NCBI Accession #

NP_001229734.2

UniProt Primary Accession #

Q58F21

UniProt Secondary Accession #

O14789; Q05DQ4; Q6P5T1; Q7Z4A6; Q8IWI6; A6NF68; B7Z811; B7Z890; B7ZAX7; D3DT32

UniProt Related Accession #

Q58F21

GenBank Nucleotide #

NM_001242805.2

NCBI Official Full Name

bromodomain testis-specific protein isoform b

NCBI Official Synonym Full Names

bromodomain, testis-specific

NCBI Official Symbol

BRDT

NCBI Official Synonym Symbols

CT9; BRD6

UniProt Protein Name

Bromodomain testis-specific protein

UniProt Synonym Protein Names

Cancer/testis antigen 9; CT9; RING3-like protein

Protein Family

Bromodomain testis-specific protein

UniProt Gene Name

BRDT

UniProt Synonym Gene Names

CT9

UniProt Entry Name

BRDT_HUMAN

NCBI Protein Information

bromodomain testis-specific protein

NCBI Summary for BRDT

BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Several transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

UniProt Comments for BRDT

BRDT: an atypical protein kinase of the BRD family. Possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. A testis-specific protein that is also expressed at a high level in non-small cell lung cancer

Protein type: Cancer Testis Antigen (CTA); Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, atypical; ATYPICAL group; BRD family

Chromosomal Location of Human Ortholog: 1p22.1

Cellular Component: nucleus

Molecular Function: histone binding; transcription coactivator activity

Biological Process: chromatin remodeling; transcription, DNA-dependent; male meiosis I; regulation of RNA splicing; RNA splicing; spermatogenesis; mRNA processing; cell differentiation; male meiosis; positive regulation of transcription, meiotic

Research Articles on BRDT

1. assessment of rs3088232 frequency in large group of non-obstructive azoospermia men and fertile controls demonstrated no significant difference between them; conclude that testicular impairments observed were not a consequence of BRDT gene mutation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BRDT antibody

Reference Product	PubMed Publications
SMARCE1 antibody	>1 publications with BRDT and SMARCE1
HIST1H1T antibody	>1 publications with BRDT and HIST1H1T

Diseases associated with anti-BRDT antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>2 publications with BRDT and Inflammation
Urogenital Abnormalities Antibodies	>1 publications with BRDT and Urogenital Abnormalities
Mental Disorders Antibodies	>1 publications with BRDT and Mental Disorders
Disease Models, Animal Antibodies	>1 publications with BRDT and Disease Models, Animal
Hemorrhage Antibodies	>1 publications with BRDT and Hemorrhage
Fibrosis Antibodies	>1 publications with BRDT and Fibrosis

Organs/Tissues associated with anti-BRDT antibody

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>29 publications with BRDT and Testis
Muscle Antibodies	>2 publications with BRDT and Muscle
Brain Antibodies	>2 publications with BRDT and Brain