Rabbit Anti-MDC Polyclonal Antibody – Cat# MBS840782

MDC Antibody – Rabbit Polyclonal

Name: MDC Antibody; Polyclonal; Rabbit; Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS840782
Price: 390 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840782

Background: MDC (macrophage-derived chemokine) is a 69-amino acid CC chemokine with a N-terminal sequence of 24 residues as a signal sequence. It was originally cloned from human monocyte-derived macrophages. Recombinant MDC attracts monocyte-derived… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

MDC, Polyclonal Antibody

Full Product Name

MDC Antibody

Product Gene Name

anti-MDC antibody

Product Synonym Names

Macrophage-derived chemokine; C-C motif chemokine 22; Stimulated T-cell chemotactic protein 1; CC chemokine STCP-1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Mouse, Rat

Form/Format

100 ug (0.5 mg/ml) affinity purified rabbit anti-mouse MDC polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Appearance: Colorless liquid

Purity/Purification

Affinity purified

Concentration

0.5 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

10,302 Da

Immunogen

E. coli-expressed mouse MDC

Handling

The antibody solution should be gently mixed before use.

Applications Tested/Suitable for anti-MDC antibody

Western Blot (WB)

Application Notes for anti-MDC antibody

Western blot analysis (0.5-4 ug/ml). However, the optimal conditions should be determined individually. Rat spleen tissue lysate can be used as a positive control.

Other Notes

Small volumes of anti-MDC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MDC purchase

MBS840782 is an antibody targeting MDC. Also known as MDC Antibody. Reactive in Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MDC. It may not necessarily be applicable to this product.

NCBI GI #

5757694

NCBI GeneID

20299

NCBI Accession #

AAD50547

UniProt Related Accession #

O88430

NCBI Official Full Name

macrophage-derived chemokine MDC/ABCD-1

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 22

NCBI Official Symbol

Ccl22

NCBI Official Synonym Symbols

MDC; DCBCK; ABCD-1; Scya22

UniProt Protein Name

C-C motif chemokine 22

UniProt Synonym Protein Names

Activated B and dendritic cell-derived; CC chemokine ABCD-1; Small-inducible cytokine A22

Protein Family

Disintegrin and metalloproteinase domain-containing protein

UniProt Gene Name

Ccl22

UniProt Synonym Gene Names

Abcd1; Scya22

UniProt Entry Name

CCL22_MOUSE

NCBI Protein Information

C-C motif chemokine 22

UniProt Comments for MDC

CCL22: May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted, signal peptide; Chemokine; Secreted; Motility/polarity/chemotaxis

Cellular Component: extracellular space; extracellular region

Molecular Function: chemokine activity; cytokine activity

Biological Process: immune response; chemotaxis; inflammatory response

Research Articles on MDC

1. CCL22 has a role in Treg skin homing to suppress depigmentation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MDC antibody

Reference Product	PubMed Publications
Ccl17 antibody	>368 publications with MDC and Ccl17
Ccr4 antibody	>233 publications with MDC and Ccr4
Ccl5 antibody	>92 publications with MDC and Ccl5
Ccl3 antibody	>66 publications with MDC and Ccl3
Ccl11 antibody	>60 publications with MDC and Ccl11
Ccl4 antibody	>55 publications with MDC and Ccl4
Ccr7 antibody	>43 publications with MDC and Ccr7
Ccl7 antibody	>24 publications with MDC and Ccl7
Ccr1 antibody	>17 publications with MDC and Ccr1

Diseases associated with anti-MDC antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>203 publications with MDC and Inflammation
Hypersensitivity Antibodies	>148 publications with MDC and Hypersensitivity
Respiratory Tract Diseases Antibodies	>121 publications with MDC and Respiratory Tract Diseases
Lung Diseases Antibodies	>106 publications with MDC and Lung Diseases
Necrosis Antibodies	>81 publications with MDC and Necrosis
Dermatitis, Atopic Antibodies	>77 publications with MDC and Dermatitis, Atopic
Respiratory Hypersensitivity Antibodies	>65 publications with MDC and Respiratory Hypersensitivity
Liver Diseases Antibodies	>18 publications with MDC and Liver Diseases
Pneumonia Antibodies	>16 publications with MDC and Pneumonia
Cardiovascular Diseases Antibodies	>15 publications with MDC and Cardiovascular Diseases

Organs/Tissues associated with anti-MDC antibody

Organ/Tissue Name	Pubmed Publications
Thymus Antibodies	>138 publications with MDC and Thymus
Skin Antibodies	>132 publications with MDC and Skin
Lymph Node Antibodies	>67 publications with MDC and Lymph Node
Spleen Antibodies	>34 publications with MDC and Spleen
Thyroid Antibodies	>3 publications with MDC and Thyroid
Salivary Gland Antibodies	>3 publications with MDC and Salivary Gland