Rabbit Anti-ACADS Polyclonal Antibody – Cat# MBS841086

ACADS Antibody – Rabbit Polyclonal

Name: ACADS Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS841086
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841086

Background: ACADS (acyl-Coenzyme A dehydrogenase), is a homotetrameric mitochondrial flavoprotein that belongs to the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutation of… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

ACADS, Polyclonal Antibody

Full Product Name

ACADS Antibody

Product Gene Name

anti-ACADS antibody

Product Synonym Names

Short-chain specific acyl-CoA dehydrogenase; Butyryl-CoA dehydrogenase

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

100 ug (0.5 mg/ml) affinity purified rabbit anti-ACADS polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Appearance: Colorless liquid

Purity/Purification

Affinity purified

Concentration

0.5 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

44,765 Da

3D Structure

ModBase 3D Structure for P15651

Immunogen

Synthetic peptide surrounding amino acid 380 of rat ACADS

Positive Control

Jurkat cell lysate and rat kidney tissue lysate

Handling

The antibody solution should be gently mixed before use.

Product Categories/Family for anti-ACADS antibody

Diabetes; Obesity & Metabolic Syndrome; Lipid Metabolism; AntibodiesAntibodies & Supporting Tools; Primary Antibodies (A-Z)

Applications Tested/Suitable for anti-ACADS antibody

Western Blot (WB)

Application Notes for anti-ACADS antibody

Western Blot analysis (1-4 ug/ml). However, the optimal concentrations should be determined individually. Blocking peptide is available separately.

Other Notes

Small volumes of anti-ACADS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ACADS purchase

MBS841086 is an antibody targeting ACADS. Also known as ACADS Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ACADS. It may not necessarily be applicable to this product.

NCBI GI #

11968090

NCBI GeneID

64304

NCBI Accession #

NP_071957.1

UniProt Primary Accession #

P15651

UniProt Related Accession #

P15651

GenBank Nucleotide #

NM_022512.2

NCBI Official Full Name

short-chain specific acyl-CoA dehydrogenase, mitochondrial

NCBI Official Synonym Full Names

acyl-CoA dehydrogenase, C-2 to C-3 short chain

NCBI Official Symbol

Acads

NCBI Official Synonym Symbols

Scad

UniProt Protein Name

Short-chain specific acyl-CoA dehydrogenase, mitochondrial

UniProt Synonym Protein Names

Butyryl-CoA dehydrogenase

Protein Family

Short-chain specific acyl-CoA dehydrogenase

UniProt Gene Name

Acads

UniProt Synonym Gene Names

SCAD

UniProt Entry Name

ACADS_RAT

NCBI Protein Information

short-chain specific acyl-CoA dehydrogenase, mitochondrial

UniProt Comments for ACADS

ACADS: Defects in ACADS are the cause of acyl-CoA dehydrogenase short-chain deficiency (ACADSD). It is an autosomal recessive disorder resulting in acute acidosis and muscle weakness in infants, and a form of lipid-storage myopathy in adults. Belongs to the acyl-CoA dehydrogenase family.

Protein type: Lipid-binding; Mitochondrial; Oxidoreductase; Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 1.3.8.1; Lipid Metabolism - fatty acid; Carbohydrate Metabolism - butanoate

Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial membrane; nucleus

Molecular Function: acyl-CoA dehydrogenase activity; butyryl-CoA dehydrogenase activity; FAD binding; acyl-CoA binding

Biological Process: response to starvation; fatty acid beta-oxidation; response to glucocorticoid stimulus; fatty acid beta-oxidation using acyl-CoA dehydrogenase; butyrate catabolic process; protein homotetramerization

Research Articles on ACADS

1. the phosphorylation of ERK1/2 inhibited the expression and activity of SCAD through the PPARalpha signaling pathway, which induced the development of pathological cardiomyocyte hypertrophy.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ACADS antibody

Reference Product	PubMed Publications
Echs1 antibody	>4 publications with ACADS and Echs1
Acat1 antibody	>2 publications with ACADS and Acat1
Acaa2 antibody	>2 publications with ACADS and Acaa2
Ehhadh antibody	>1 publications with ACADS and Ehhadh
Hadhb antibody	>1 publications with ACADS and Hadhb

Pathways associated with anti-ACADS antibody

Products by Pathway	Pathway Diagram
Beta Oxidation Meta Pathway antibodies	Beta Oxidation Meta Pathway Diagram
Beta Oxidation Of Butanoyl-CoA To Acetyl-CoA Pathway antibodies	Beta Oxidation Of Butanoyl-CoA To Acetyl-CoA Pathway Diagram
Beta Oxidation Of Hexanoyl-CoA To Butanoyl-CoA Pathway antibodies	Beta Oxidation Of Hexanoyl-CoA To Butanoyl-CoA Pathway Diagram
Butanoate Metabolism Pathway antibodies	Butanoate Metabolism Pathway Diagram
Butanoate Metabolism Pathway antibodies	Butanoate Metabolism Pathway Diagram
Carbon Metabolism Pathway antibodies	Carbon Metabolism Pathway Diagram
Carbon Metabolism Pathway antibodies	Carbon Metabolism Pathway Diagram
Fatty Acid Beta Oxidation Pathway antibodies	Fatty Acid Beta Oxidation Pathway Diagram
Fatty Acid Beta Oxidation 2 Pathway antibodies	Fatty Acid Beta Oxidation 2 Pathway Diagram
Fatty Acid Beta Oxidation 3 Pathway antibodies	Fatty Acid Beta Oxidation 3 Pathway Diagram

Diseases associated with anti-ACADS antibody

Disease Name	Pubmed Publications
Short chain Acyl CoA dehydrogenase deficiency Antibodies	>10 publications with ACADS and Short chain Acyl CoA dehydrogenase deficiency
Fatty Liver Antibodies	>6 publications with ACADS and Fatty Liver
Liver Diseases Antibodies	>5 publications with ACADS and Liver Diseases
Brain Diseases Antibodies	>4 publications with ACADS and Brain Diseases
Nervous System Diseases Antibodies	>2 publications with ACADS and Nervous System Diseases
Heart Diseases Antibodies	>2 publications with ACADS and Heart Diseases
Cardiovascular Diseases Antibodies	>2 publications with ACADS and Cardiovascular Diseases
Disease Models, Animal Antibodies	>1 publications with ACADS and Disease Models, Animal
Atherosclerosis Antibodies	>1 publications with ACADS and Atherosclerosis
Kidney Diseases Antibodies	>1 publications with ACADS and Kidney Diseases

Organs/Tissues associated with anti-ACADS antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>11 publications with ACADS and Liver
Brain Antibodies	>7 publications with ACADS and Brain
Heart Antibodies	>5 publications with ACADS and Heart
Adipose Tissue Antibodies	>4 publications with ACADS and Adipose Tissue
Kidney Antibodies	>3 publications with ACADS and Kidney
Pancreas Antibodies	>1 publications with ACADS and Pancreas
Prostate Antibodies	>1 publications with ACADS and Prostate