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AZD-9291

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841928

Background: AZD-9291 is a potent, third generation, mutant-selective EGFR tyrosine kinase inhibitor. It is effective against both EGFR-TKI sensitizing and resistance T790M mutations. Displays anticancer properties. More details

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Product Documentation
PDF
Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AZD-9291, Biochemical
Full Product Name
AZD-9291
Product Gene Name
AZD-9291 biochemical
Product Synonym Names
N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]- 2-propenamide
Form/Format
Appearance: Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
499.61
CAS Number
1421373-65-0
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
71496458
Solubility/Reconstitution Instructions
DMSO (>50 mg/ml)
SMILES
CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC
InChi
 InChI=1S/C28H33N7O2/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32)
InChi Key
DUYJMQONPNNFPI-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for AZD-9291 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase InhibitorsBiochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase InhibitorsSignaling Pathways; EGFR Signaling; EGFR InhibitorsBiochemicals; Biochemicals (A

Structure of AZD-9291 biochemical

AZD-9291 Biochemical – Cat# MBS841928

Other Notes

Small volumes of AZD-9291 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZD-9291 purchase

MBS841928 is a biochemical targeting AZD-9291.
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