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LY-341495

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842109

Background: LY341495 is a potent, brain-permeable, and selective antagonist of the group II metabotropic glutamate receptors (mGluR), mGluR2 and mGluR3 (IC??s = 21 and 14 nM, respectively, for human isoforms). It less effectively blocks mGluR8 and mGluR7… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
LY-341495, Biochemical
Full Product Name
LY-341495
Product Gene Name
LY-341495 biochemical
Product Synonym Names
2S)-2-Amino-2-[(1S,2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl) propanoic acid
Form/Format
Appearance: Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
353.37
CAS Number
201943-63-7
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD00949707
PubChem CID
9819927
Solubility/Reconstitution Instructions
DMSO (~ 3 mg/ml with slight warming)
SMILES
C1C(C1C(CC2C3=CC=CC=C3OC4=CC=CC=C24)(C(=O)O)N)C(=O)O
InChi
InChI=1S/C20H19NO5/c21-20(19(24)25,15-9-13(15)18(22)23)10-14-11-5-1-3-7-16(11)26-17-8-4-2-6-12(14)17/h1-8,13-15H,9-10,21H2,(H,22,23)(H,24,25)/t13-,15-,20-/m0/s1
InChi Key
VLZBRVJVCCNPRJ-KPHUOKFYSA-N
Handling
Protect from air and light

Product Categories/Family for LY-341495 biochemical

Enzyme Inhibitors; Glutamate Receptor AntagonistsEnzyme Inhibitors; Enzyme Inhibitors (A-Z) Biochemicals; Enzyme Inhibitors; Glutamate Receptor AntagonistsBiochemicals; Enzyme Inhibitors; Enzyme Inhibitors (A-Z) Biochemicals; Biochemicals (A-Z)

Structure of LY-341495 biochemical

LY-341495 Biochemical – Cat# MBS842109

Other Notes

Small volumes of LY-341495 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LY-341495 purchase

MBS842109 is a biochemical targeting LY-341495.
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