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NVP-BHG712

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842128

Background: A potent, selective small-molecule inhibitor of the receptor tyrosine kinase EphB4 (ED?? = 25 nM). Displays selectivity for EphB4 over >40 other kinases in vitro, including FGFR3. NVP-BHG712 blocks Ephrin receptor autophosphorylation and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
NVP-BHG712, Biochemical
Full Product Name
NVP-BHG712
Product Gene Name
NVP-BHG712 biochemical
Product Synonym Names
4-Methyl-3-[[1-methyl-6-(3-pyridiny l)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino]-N-[3-(t rifluoromethyl)phenyl]benzamide
Form/Format
Appearance: Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
503.48
CAS Number
940310-85-0
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
16747388
Solubility/Reconstitution Instructions
DMSO (> 100 mg/ml)
SMILES
CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC3=NC(=NC4=C3C=NN4C)C5=CN=Canonical SMILES : CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC3=NC(=NC4=C3C=NN4C)C5=CN=CC=C5
InChi
InChI=1S/C26H20F3N7O/c1-15-8-9-16(25(37)32-19-7-3-6-18(12-19)26(27,28)29)11-21(15)33-23-20-14-31-36(2)24(20)35-22(34-23)17-5-4-10-30-13-17/h3-14H,1-2H3,(H,32,37)(H,33,34,35)
InChi Key
ZCCPLJOKGAACRT-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for NVP-BHG712 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors and Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of NVP-BHG712 biochemical

NVP-BHG712 Biochemical – Cat# MBS842128

Other Notes

Small volumes of NVP-BHG712 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NVP-BHG712 purchase

MBS842128 is a biochemical targeting NVP-BHG712.
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