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AMG-208

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842129

Background: AMG-708 is a selective small-molecule inhibitor (IC?? = 9.3 nM) of the proto-oncogene c-Met with potential antineoplastic activity. AMG 208 inhibits the ligand-dependent and ligand-independent activation of c-Met, inhibiting its tyrosine kinase… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AMG-208, Biochemical
Full Product Name
AMG-208
Product Gene Name
AMG-208 biochemical
Product Synonym Names
7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
383.4
CAS Number
1002304-34-8
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
24864821
Solubility/Reconstitution Instructions
DMSO (~ 1 mg in ml) or EtOH (~ 1 mg/ml)
SMILES
COC1=CC2=NC=CC(=C2C=C1)OCC3=NN=C4N3N=C(C=C4)C5=CC=CC=C5
InChi
InChI=1S/C22H17N5O2/c1-28-16-7-8-17-19(13-16)23-12-11-20(17)29-14-22-25-24-21-10-9-18(26-27(21)22)15-5-3-2-4-6-15/h2-13H,14H2,1H3
InChi Key
HEAIZQNMNCHNFD-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for AMG-208 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors and Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of AMG-208 biochemical

AMG-208 Biochemical – Cat# MBS842129

Other Notes

Small volumes of AMG-208 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AMG-208 purchase

MBS842129 is a biochemical targeting AMG-208.
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