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Oprozomib

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842240

Background: Oprozomib is a next generation, irreversible and selective proteasome inhibitor that displays potent anti-myeloma properties. It potently induces apoptosis in HNSCC cell lines via upregulation of pro-apoptotic Bik. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Oprozomib, Biochemical
Full Product Name
Oprozomib
Product Synonym Names
N-((S)-3-methoxy-1-(((S)-3-methoxy-1-(((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)-2-methylthiazole-5-carboxamide; ONX-0912; PR-047
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
532.61
CAS Number
935888-69-0
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
25067547
Solubility/Reconstitution Instructions
DMSO (~100 mg/ml)
SMILES
CC1=NC=C(S1)C(=O)NC(COC)C(=O)NC(COC)C(=O)NC(CC2=CC=CC=C2)C(=O)C3(CO3)C
InChi
InChI=1S/C25H32N4O7S/c1-15-26-11-20(37-15)24(33)29-19(13-35-4)23(32)28-18(12-34-3)22(31)27-17(21(30)25(2)14-36-25)10-16-8-6-5-7-9-16/h5-9,11,17-19H,10,12-14H2,1-4H3,(H,27,31)(H,28,32)(H,29,33)/t17-,18-,19-,25+/m0/s1
InChi Key
SWZXEVABPLUDIO-WSZYKNRRSA-N
Handling
Protect from light and moisture

Product Categories/Family for Oprozomib biochemical

Enzyme Inhibitors; Proteasome Inhibitors and Biochemicals; Enzyme Inhibitors; Proteasome Inhibitors and Enzyme Inhibitors; Ubiquitin Proteasome Pathway Inhibitors and Biochemicals; Enzyme Inhibitors; Ubiquitin Proteasome Pathway Inhibitors and Signaling P

Structure of Oprozomib biochemical

Oprozomib Biochemical – Cat# MBS842240

Other Notes

Small volumes of Oprozomib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Oprozomib purchase

MBS842240 is a biochemical targeting Oprozomib.
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