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Calpain Inhibitor II, ALLM (Ac-LLM-CHO)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842245

Background: A cell-permeable inhibitor of calpain 1 (Ki = 120 nM) and calpain 2 (Ki = 230 nM). Also potently inhibits cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM). Shown to induce caspase-dependent apoptosis in human acute lymphoblastic leukemia… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Calpain Inhibitor II, ALLM, Biochemical
Full Product Name
Calpain Inhibitor II, ALLM
Product Synonym Names
Ac-LLM-CHO; N-Acetyl-Leu-Leu-Methional
Sequence
N-Acetyl-L eu-Leu-Met hional
Form/Format
Appearance: White powder
Purity/Purification
>=95% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
401.57
CAS Number
136632-32-1
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD00065506
PubChem CID
4331
Solubility/Reconstitution Instructions
DMSO (25 mg/ml) or EtOH (25 mg/ml)
SMILES
CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCSC)C=O)NC(=O)C
InChi
InChI=1S/C19H35N3O4S/c1-12(2)9-16(20-14(5)24)19(26)22-17(10-13(3)4)18(25)21-15(11-23)7-8-27-6/h11-13,15-17H,7-10H2,1-6H3,(H,20,24)(H,21,25)(H,22,26)
InChi Key
RJWLAIMXRBDUMH-UHFFFAOYSA-N
Handling
Protect from moisture and air

Other Notes

Small volumes of Calpain Inhibitor II, ALLM biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS842245 is a biochemical targeting Calpain Inhibitor II, ALLM.
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