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OSI-027

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842313

Background: OSI-027 is a potent mammalian target of rapamycin (mTOR) kinase inhibitor with potential antineoplastic activity. It binds to and inhibits both the raptor-mTOR (TOR complex 1 or TORC1) and the rictor-mTOR (TOR complex 2 or TORC2) complexes of… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
OSI-027, Biochemical
Full Product Name
OSI-027
Product Gene Name
OSI-027 biochemical
Product Synonym Names
4-(4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl)cyclohexanecarboxylic acid; ASP4786
Form/Format
Appearance: Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
406.44
CAS Number
936890-98-1
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD20275101
PubChem CID
44224160
Solubility/Reconstitution Instructions
DMSO (~18 mg/ml)
SMILES
COC1=CC=CC2=CC(=C3C4=C(N=CNN4C(=N3)C5CCC(CC5)C(=O)O)N)N=C21
InChi
InChI=1S/C21H22N6O3/c1-30-15-4-2-3-13-9-14(25-16(13)15)17-18-19(22)23-10-24-27(18)20(26-17)11-5-7-12(8-6-11)21(28)29/h2-4,9-12H,5-8,22H2,1H3,(H,23,24)(H,28,29)/b17-14-
InChi Key
CDNMDRUIGNHEMR-VKAVYKQESA-N
Handling
Protect from light and moisture

Product Categories/Family for OSI-027 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; mTOR Inhibitors and Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; mTOR Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of OSI-027 biochemical

OSI-027 Biochemical – Cat# MBS842313

Other Notes

Small volumes of OSI-027 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OSI-027 purchase

MBS842313 is a biochemical targeting OSI-027.
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