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Caspase-8 Substrate IETD-AFC (Ac-IETD-AFC)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842320

Background: Ready-to-use fluorometric substrate for FLICE/caspase-8 and related caspases that recognize the amino acid sequence IETD. The sequence IETD is based on caspase-8 cleavage site in CPP32/caspase-3 proenzyme. FLICE and related caspase activity can be… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Caspase-8 Substrate IETD-AFC, Biochemical
Full Product Name
Caspase-8 Substrate IETD-AFC
Product Synonym Names
Ac-IETD-AFC; Caspase-8 Substrate; Fluorogenic
Sequence
Ac-Ile-Glu -Thr-Asp-A FC
Form/Format
DMSO (2 mM)
Appearance: Liquid
Purity/Purification
>95% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
729.7
Structure Available?
No
Salt Form
No
Cell-Permeable?
No
PubChem CID
25108570
SMILES
CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)C(F)(F)F)NC(=O)C
InChi
InChI=1S/C31H38F3N5O12/c1-5-13(2)25(35-15(4)41)29(49)37-19(8-9-22(42)43)27(47)39-26(14(3)40)30(50)38-20(12-23(44)45)28(48)36-16-6-7-17-18(31(32,33)34)11-24(46)51-21(17)10-16/h6-7,10-11,13-14,19-20,25-26,40H,5,8-9,12H2,1-4H3,(H,35,41)(H,36,48)(H,37,49)(H,38,50)(H,39,47)(H,42,43)(H,44,45)/t13-,14+,19-,20-,25-,26-/m0/s1
InChi Key
CGUOWXRXLQXOKO-FCQBACSVSA-N
Handling
Protect from light and moisture

Other Notes

Small volumes of Caspase-8 Substrate IETD-AFC biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Caspase-8 Substrate IETD-AFC purchase

MBS842320 is a biochemical targeting Caspase-8 Substrate IETD-AFC.
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