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Epoxomicin

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842540

Background: Originally isolated from Actinomycetes strain based on its potent in vivo antitumor activity, Epoxomicin is a potent, cell-permeable, selective and irreversible proteasome inhibitor. More potent inhibitor of the chymotrypsin-like activity of the… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Epoxomicin, Biochemical
Full Product Name
Epoxomicin
Product Synonym Names
N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-[(1S)-3-methyl- 1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-L-threoninamide; BU-4061T
Form/Format
Appearance: White solid
Purity/Purification
>=95% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
554.7
CAS Number
134381-21-8
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD03791061
PubChem CID
11226684
Solubility/Reconstitution Instructions
DMSO (~ 10 mg/ml)
SMILES
CCC(C)C(C(=O)NC(C(C)O)C(=O)NC(CC(C)C)C(=O)C1(CO1)C)NC(=O)C(C(C)CC)N(C)C(=O)C
InChi
InChI=1S/C28H50N4O7/c1-11-16(5)21(30-27(38)23(17(6)12-2)32(10)19(8)34)25(36)31-22(18(7)33)26(37)29-20(13-15(3)4)24(35)28(9)14-39-28/h15-18,20-23,33H,11-14H2,1-10H3,(H,29,37)(H,30,38)(H,31,36)/t16-,17-,18+,20-,21-,22-,23-,28+/m0/s1
InChi Key
DOGIDQKFVLKMLQ-JTHVHQAWSA-N
Handling
Protect from air and moisture

Product Categories/Family for Epoxomicin biochemical

Enzyme Inhibitors; Proteasome Inhibitors and Biochemicals; Enzyme Inhibitors; Proteasome Inhibitors and Biochemicals (A-Z)

Structure of Epoxomicin biochemical

Epoxomicin Biochemical – Cat# MBS842540

Other Notes

Small volumes of Epoxomicin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Epoxomicin purchase

MBS842540 is a biochemical targeting Epoxomicin.
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