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Tyrphostin AG 490

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842805

Background: Selectively inhibits EGF receptor auto-phosphorylation (IC?? = 100 uM) and selectively inhibits DNA synthesis and cell growth; induces apoptosis. A JAK2 inhibitor. Blocks growth of leukemia cells in vivo and in vitro. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Tyrphostin AG 490, Biochemical
Full Product Name
Tyrphostin AG 490
Product Synonym Names
2-Cyano-3-(3,4-dihydroxyphenyl)-N-(benzyl)-2-propenamide; 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide; AG 490
Form/Format
Appearance: Off-white solid
Purity/Purification
>=99%
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
294.31
CAS Number
133550-30-8
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD00236452
PubChem CID
5328779
Solubility/Reconstitution Instructions
DMSO (100 mM) and ETOH (20 mM)
SMILES
C1=CC=C(C=C1)CNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
InChi
InChI=1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+
InChi Key
TUCIOBMMDDOEMM-RIYZIHGNSA-N
Handling
Protect from light and air

Structure of Tyrphostin AG 490 biochemical

Tyrphostin Ag 490 Biochemical – Cat# MBS842805

Other Notes

Small volumes of Tyrphostin AG 490 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tyrphostin AG 490 purchase

MBS842805 is a biochemical targeting Tyrphostin AG 490.
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